Giuseppe
Emeritus
[Source: PLoS ONE, full page: (LINK). Abstract, edited.]
Research Article
Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011
Le Phan Kim Thoa, Pai-Shan Chiang, Truong Huu Khanh, Shu-Ting Luo, Tran Ngoc Hanh Dan, Ya-Fang Wang, Tang Chi Thuong, Wan-Yu Chung, Nguyen Thanh Hung, Jen-Ren Wang, Le Nguyen Thanh Nhan, Le Quoc Thinh, Ih-Jen Su, Than Duc Dung, Min-Shi Lee
Abstract
Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.
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Citation: Thoa LPK, Chiang P-S, Khanh TH, Luo S-T, Dan TNH, et al. (2013) Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011. PLoS ONE 8(7): e69895.
doi:10.1371/journal.pone.0069895
Editor: Xiao-Fang Yu, Johns Hopkins School of Public Health, United States of America
Received: January 28, 2013; Accepted: June 13, 2013; Published: July 29, 2013
Copyright: ? 2013 Thoa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: The project was funded by National Health Research Institutes, Taiwan. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: The authors have declared that no competing interests exist.
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Research Article
Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011
Le Phan Kim Thoa, Pai-Shan Chiang, Truong Huu Khanh, Shu-Ting Luo, Tran Ngoc Hanh Dan, Ya-Fang Wang, Tang Chi Thuong, Wan-Yu Chung, Nguyen Thanh Hung, Jen-Ren Wang, Le Nguyen Thanh Nhan, Le Quoc Thinh, Ih-Jen Su, Than Duc Dung, Min-Shi Lee
Abstract
Enterovirus 71 (EV71) frequently causes fatal infections in young children in Asia. In 2011, EV71 epidemics occurred in southern Vietnam. We conducted genetic and antigenic analysis of the EV71 isolates and found that 94% of them were genotype C4a related to two lineages circulating in China and 6% were genotype C5 which have circulated in Vietnam since 2003. Antigenic variants were not detected. EV71 vaccines are being developed. Longitudinal enterovirus surveillance data are critical to formulate vaccination policy in Vietnam.
________
Citation: Thoa LPK, Chiang P-S, Khanh TH, Luo S-T, Dan TNH, et al. (2013) Genetic and Antigenic Characterization of Enterovirus 71 in Ho Chi Minh City, Vietnam, 2011. PLoS ONE 8(7): e69895.
doi:10.1371/journal.pone.0069895
Editor: Xiao-Fang Yu, Johns Hopkins School of Public Health, United States of America
Received: January 28, 2013; Accepted: June 13, 2013; Published: July 29, 2013
Copyright: ? 2013 Thoa et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: The project was funded by National Health Research Institutes, Taiwan. The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: The authors have declared that no competing interests exist.
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