tetano
Editor, Senior Moderator
Infect Genet Evol. 2013 Sep 20. pii: S1567-1348(13)00342-0. doi: 10.1016/j.meegid.2013.09.004. [Epub ahead of print]
Perspective on emergence and re-emergence of amantadine resistant influenza A viruses in domestic animals in China.
Wan XF, Carrel M, Long LP, Alker AP, Emch M.
Source
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 300045, China;; Pathogen Diagnostic Center, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, the United States of America. Electronic address: wan@cvm.msstate.edu.
Abstract
In China, approximately 20% of the animal original influenza A viruses have molecular markers of amantadine resistance. Through phylogenetic data analyses and geospatial statistical analyses, this study suggests emergence of amantadine resistance in animal influenza could be due to selection pressures in China, for example, amantadine usage in some areas.
Copyright ? 2013 Elsevier B.V. All rights reserved.
KEYWORDS:
Amantadine resistance, Animal origin influenza A virus, Drug resistance, Influenza A virus, geospatial analysis, phylogenetic analysis
PMID:
24060734
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24060734
Perspective on emergence and re-emergence of amantadine resistant influenza A viruses in domestic animals in China.
Wan XF, Carrel M, Long LP, Alker AP, Emch M.
Source
College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 300045, China;; Pathogen Diagnostic Center, Key Laboratory of Molecular Virology and Immunology, Institut Pasteur of Shanghai, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200025, China; Department of Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi State, MS 39762, the United States of America. Electronic address: wan@cvm.msstate.edu.
Abstract
In China, approximately 20% of the animal original influenza A viruses have molecular markers of amantadine resistance. Through phylogenetic data analyses and geospatial statistical analyses, this study suggests emergence of amantadine resistance in animal influenza could be due to selection pressures in China, for example, amantadine usage in some areas.
Copyright ? 2013 Elsevier B.V. All rights reserved.
KEYWORDS:
Amantadine resistance, Animal origin influenza A virus, Drug resistance, Influenza A virus, geospatial analysis, phylogenetic analysis
PMID:
24060734
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24060734