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Pediatric Critical Care Medicine: Fulminant Myocarditis Associated With H1n1 Virus: Case Report and Literature Review

tetano

Editor, Senior Moderator
Pediatric Critical Care Medicine:
May 2014 - Volume 15 - Issue 4_suppl - p 187
doi: 10.1097/01.pcc.0000449565.64468.2f
Abstracts of the 7th World Congress on Pediatric Critical Care, May 4-7, 2014 Istanbul, Turkey


Abstract 839: Fulminant Myocarditis Associated With H1n1 Virus: Case Report and Literature Review

Saraiva, M.1; Taguchi, A.2; Gaspar, H.A.1; Ferranti, J.F.1; Carvalho, W.B.1; Delgado, A.F.1
Free Access
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1Pediatric Intensive Care Unit, University of S?o Paulo Medical School, S?o Paulo, Brazil 2Pediatrics, University of S?o Paulo Medical School, S?o Paulo, Brazil

Background and aims: The role of Influenza A virus subtype H1N1 in the acute myocarditis pathogenesis has been established.

Aims: To report a case of fulminant myocarditis associated with H1N1 influenza virus, describing the importance of this virus in fulminant myocarditis etiology, the available treatments and potential outcomes for this pathology and to highlight the importance of echocardiography to the cardiac dysfunction diagnosis at the bedside.

Methods: Reporting the case of one 4 years old patient, with cardiogenic shock and polymerase chain reaction positive to Influenza H1N1 virus and discussed about the clinical findings, laboratory tests, imaging and pathological examinations.

Results: This patient had severe fulminant myocarditis evolution, with hemodynamic instability and no response to the clinical treatment despite the early diagnosis.

Conclusions: The H1N1 virus should always be regarded as one of the causes of myocarditis and relevant characteristics such as seasonality, endemic situation and vaccine coverage should be considered. Despite intensive treatment the mortality of fulminant myocarditis is high. Mechanical circulatory support using extracorporeal membrane oxygenation (ECMO) in patients with rapidly progressive heart failure and cardiogenic shock unresponsive to medical treatment seems to reduce significantly this mortality.

?2014The Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

http://journals.lww.com/pccmjournal...9___Fulminant_Myocarditis_Associated.836.aspx
 
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