tetano
Editor, Senior Moderator
Pediatr Diabetes
. 2020 Nov 17.
doi: 10.1111/pedi.13158. Online ahead of print.
Children and youth with diabetes are not at increased risk for hospitalization due to COVID-19
Roque Cardona-Hernandez[SUP] 1 [/SUP], Valentino Cherubini[SUP] 2 [/SUP], Dario Iafusco[SUP] 3 [/SUP], Riccardo Schiaffini[SUP] 4 [/SUP], Xiaoping Luo[SUP] 5 [/SUP], David M Maahs[SUP] 6 [/SUP]
Affiliations
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), responsible for the coronavirus disease COVID-19, was first identified in Wuhan, China in December 2019. Diabetes, as well as other cardiovascular comorbidities, has been recognized as a major risk factor for outcomes and mortality in adults with COVID19, particularly in the elderly with type 2 diabetes. Based on these conclusions, COVID-19 data on adults have been generalizedto youth with diabetes. Nevertheless, experience from Pediatric Diabetes practices in China (Wuhan), Italy, Spain (Catalonia) and the US (San Francisco Bay Area) consistently report only a single severe case of COVID-19 in a 20-year-old female youth with type 1 diabetes (T1D) that was hospitalized for bilateral pneumonia and was subsequently discharged without complications. In Italy, information on COVID-19 in all children with diabetes is collected on a weekly basis andthose with positive swab test or infection-related symptoms reported to a dedicated national registry. Of a total of 15,500 children tested,11subjects with T1D (age 8-17y) tested positive for COVID-19; 6/11 were asymptomatic and the rest presented with mild symptoms. In the rest of locations, youth with T1D diagnosed with COVID-19 were based on clinical suspicion and a confirmatory PCR test(Wuhan:0; Catalonia-HSJD:3; California-Stanford:2) and all of them were asymptomatic or had a mild course.We suggest that COVID-19 data from adults should not be generalizedto children, adolescents and youth with diabetes as their outcomes and prognosis seem to be similar to their non-diabetic-peers and consistently milder than adults with diabetes. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; Children; Diabetes; Outcome; Prognosis; Type 1 diabetes.
. 2020 Nov 17.
doi: 10.1111/pedi.13158. Online ahead of print.
Children and youth with diabetes are not at increased risk for hospitalization due to COVID-19
Roque Cardona-Hernandez[SUP] 1 [/SUP], Valentino Cherubini[SUP] 2 [/SUP], Dario Iafusco[SUP] 3 [/SUP], Riccardo Schiaffini[SUP] 4 [/SUP], Xiaoping Luo[SUP] 5 [/SUP], David M Maahs[SUP] 6 [/SUP]
Affiliations
- PMID: 33205546
- DOI: 10.1111/pedi.13158
Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), responsible for the coronavirus disease COVID-19, was first identified in Wuhan, China in December 2019. Diabetes, as well as other cardiovascular comorbidities, has been recognized as a major risk factor for outcomes and mortality in adults with COVID19, particularly in the elderly with type 2 diabetes. Based on these conclusions, COVID-19 data on adults have been generalizedto youth with diabetes. Nevertheless, experience from Pediatric Diabetes practices in China (Wuhan), Italy, Spain (Catalonia) and the US (San Francisco Bay Area) consistently report only a single severe case of COVID-19 in a 20-year-old female youth with type 1 diabetes (T1D) that was hospitalized for bilateral pneumonia and was subsequently discharged without complications. In Italy, information on COVID-19 in all children with diabetes is collected on a weekly basis andthose with positive swab test or infection-related symptoms reported to a dedicated national registry. Of a total of 15,500 children tested,11subjects with T1D (age 8-17y) tested positive for COVID-19; 6/11 were asymptomatic and the rest presented with mild symptoms. In the rest of locations, youth with T1D diagnosed with COVID-19 were based on clinical suspicion and a confirmatory PCR test(Wuhan:0; Catalonia-HSJD:3; California-Stanford:2) and all of them were asymptomatic or had a mild course.We suggest that COVID-19 data from adults should not be generalizedto children, adolescents and youth with diabetes as their outcomes and prognosis seem to be similar to their non-diabetic-peers and consistently milder than adults with diabetes. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; Children; Diabetes; Outcome; Prognosis; Type 1 diabetes.