tetano
Editor, Senior Moderator
Pediatr Dermatol
. 2025 May 6.
doi: 10.1111/pde.15975. Online ahead of print. Juvenile Dermatomyositis Triggered by Influenza B: A Case Report on Viral-Induced Autoimmunity
Santiago Dans-Caballero[SUP] 1 2 [/SUP], Miguel Juan-Cencerrado[SUP] 3 [/SUP], Carmen Mochón-Jiménez[SUP] 3 [/SUP], Rosa Roldán-Molina[SUP] 1 2 [/SUP], Verónica C Pérez-Guijo[SUP] 1 2 4 [/SUP]
Affiliations
A previously healthy 13-year-old boy developed juvenile dermatomyositis (JDM) shortly after a confirmed influenza B infection, presenting with progressive proximal muscle weakness and classic cutaneous findings. Laboratory tests revealed elevated muscle enzymes and myositis-specific autoantibodies, supporting the diagnosis. The temporal association suggests a potential post-viral autoimmune trigger, highlighting influenza B as a possible environmental factor in JDM pathogenesis. This case reinforces the need for heightened clinical awareness and further research into virus-associated autoimmune mechanisms in pediatric myopathies.
Keywords: dermatomyositis; immune evasion; influenza virus.
. 2025 May 6.
doi: 10.1111/pde.15975. Online ahead of print. Juvenile Dermatomyositis Triggered by Influenza B: A Case Report on Viral-Induced Autoimmunity
Santiago Dans-Caballero[SUP] 1 2 [/SUP], Miguel Juan-Cencerrado[SUP] 3 [/SUP], Carmen Mochón-Jiménez[SUP] 3 [/SUP], Rosa Roldán-Molina[SUP] 1 2 [/SUP], Verónica C Pérez-Guijo[SUP] 1 2 4 [/SUP]
Affiliations
- PMID: 40326606
- DOI: 10.1111/pde.15975
A previously healthy 13-year-old boy developed juvenile dermatomyositis (JDM) shortly after a confirmed influenza B infection, presenting with progressive proximal muscle weakness and classic cutaneous findings. Laboratory tests revealed elevated muscle enzymes and myositis-specific autoantibodies, supporting the diagnosis. The temporal association suggests a potential post-viral autoimmune trigger, highlighting influenza B as a possible environmental factor in JDM pathogenesis. This case reinforces the need for heightened clinical awareness and further research into virus-associated autoimmune mechanisms in pediatric myopathies.
Keywords: dermatomyositis; immune evasion; influenza virus.