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Pandemic flu vaccine not linked to rare nerve disorder

tetano

tetano

Editor, Senior Moderator
PARIS ? Vaccines used in the 2009 "swine flu" pandemic caused no perceptible rise in a neurological disorder called Guillain-Barre syndrome, a study published in the British Medical Journal (BMJ) said on Wednesday.

The investigation is part of a safety probe into booster-aided flu vaccines that dates back 35 years.

In 1976, immunisation against a "swine flu" virus in the United States was halted after doctors found a seven-fold increase in risk from Guillain-Barre.

Studies on subsequent seasonal virus vaccinations found either no increases or only a modest increase in risk, leaving unresolved a debate whether the flu jab could be dangerous or not.

Guillain-Barre is a disease in which the body's immune defences attacks nerve cells, causing muscle weakness and sometime paralysis. It is very rare, occurring in a range between 0.4 and four per 100,000 "person years," a measure of risk used in epidemiology. It is fatal in three to 10 percent of cases.

The study, funded by the European Centre for Disease Prevention and Control (ECDC) was done among 50 million people in five European countries where doctors had used a flu jab with a booster, also called an adjuvant, to prime the immune system.

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Re: Pandemic flu vaccine not linked to rare nerve disorder

No Substantial Link Between Swine Flu Vaccine and Guillain-Barre Syndrome, Experts Confirm

ScienceDaily (July 12, 2011) ? Adjuvanted vaccines used during the 2009 swine flu pandemic did not increase the risk of Guillain-Barr? syndrome substantially, if at all, finds a large Europe-wide study published online in the British Medical Journal (BMJ). An adjuvant is a substance added to a vaccine to stimulate the immune system to respond to the vaccine.

The study provides reassurance about potential risks of adjuvanted pandemic influenza vaccines. It also exemplifies the use of a newly available infrastructure in Europe, which may help to provide reliable risk assessments related to future concerns.

Guillain-Barr? syndrome is a rare disorder in which a person's own immune system damages the nerve cells, causing muscle weakness and sometimes paralysis.

In 1976, a vaccine used during a US flu pandemic was linked with the syndrome and vaccination was stopped abruptly. Since then, studies have shown no or only slight increases in risk but, to date, the role of flu vaccines as a trigger in Guillain-Barr? syndrome remains controversial.

http://www.sciencedaily.com/release...encedaily (ScienceDaily: Latest Science News)
 
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