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Ophthalmic Surg Lasers Imaging Retina . Increasing Incidence of Retinal Vein Occlusion Among Young Adults Following the COVID-19 Pandemic

tetano

Editor, Senior Moderator
Ophthalmic Surg Lasers Imaging Retina


. 2025 Jul 28:1-5.
doi: 10.3928/23258160-20250701-01. Online ahead of print. Increasing Incidence of Retinal Vein Occlusion Among Young Adults Following the COVID-19 Pandemic

Shivesh H Shah[SUP] #[/SUP][SUP] 1 2 [/SUP], Edward S Lu[SUP] #[/SUP][SUP] 1 2 [/SUP], Ioanna Ploumi[SUP] 1 2 [/SUP], Sandra Hoyek[SUP] 1 2 [/SUP], Kayla Nodecker[SUP] 1 2 [/SUP], Selin Gumustop[SUP] 1 2 [/SUP], Sarah L Wagner[SUP] 1 2 [/SUP], Xinyi Ding[SUP] 1 2 [/SUP], Ying Zhu[SUP] 1 2 [/SUP], Chong Chen[SUP] 1 2 [/SUP], Leo A Kim[SUP] 2 3 [/SUP], Demetrios G Vavvas[SUP] 2 3 [/SUP], Joan W Miller[SUP] 2 3 [/SUP], Deeba Husain[SUP] 2 3 [/SUP], Nimesh A Patel[SUP] 2 3 [/SUP], John B Miller[SUP] 1 2 3 [/SUP]



Affiliations
Abstract

Background and objective: Retinal vein occlusion (RVO) incidence among adults under age 50 years before and during the coronavirus disease 2019 (COVID-19) pandemic was evaluated to clarify whether COVID-19 infection increases RVO risk.
Patients and methods: This was a retrospective study of adult patients under age 50 years diagnosed with RVO between 2016 and 2023.
Results: The study included 268 patients with RVO. Cases increased from 111 (41%) pre-pandemic (2016 to 2019) to 157 (59%) post-pandemic (2020 to 2023). Incidence rose from 2.7% to 4.2% of retina clinic diagnoses (P = 0.006). Age at diagnosis did not differ (median 40.4 vs 39.6 years, P > 0.05). The youngest tertile (18 to 29 years) trended towards a greater proportion of cases post-pandemic (19.6% vs 10.6%, P = 0.20), while the oldest tertile (39 to 49 years) trended towards a smaller proportion (48.4% vs 56.1%, P = 0.42).
Conclusion: An increase in RVO incidence during COVID-19 was observed, with a trend towards younger age groups.


 
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