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Open Forum Infect Dis . Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP

tetano

tetano

Editor, Senior Moderator
Open Forum Infect Dis


. 2021 Jun 24;8(7):ofab343.
doi: 10.1093/ofid/ofab343. eCollection 2021 Jul.
Acute Immune Thrombocytopenia (ITP) Following COVID-19 Vaccination in a Patient With Previously Stable ITP


Muzamil Jawed[SUP] 1 [/SUP], Amna Khalid[SUP] 1 [/SUP], Mayer Rubin[SUP] 1 [/SUP], Ramsha Shafiq[SUP] 1 [/SUP], Nail Cemalovic[SUP] 1 [/SUP]



Affiliations

Abstract

Immune thrombocytopenia (ITP) is an autoimmune condition associated with multiple risk factors including viral infections (hepatitis B virus/hepatitis C virus/cytomegalovirus, HIV, and recently severe acute respiratory syndrome coronavirus 2) and vaccines. Though immune mechanisms have been proposed to explain the pathogenesis of acute ITP, autoimmunity with the coronavirus disease 2019 (COVID-19) vaccine is still unclear and needs further research. We report a case of acute ITP after administration of the Pfizer-BioNTech mRNA COVID-19 vaccine in a patient with previously stable ITP.

Keywords: COVID-19; Pfizer; SARS-CoV-2; immune thrombocytopenic purpura; vaccination.
 
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