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Neuropediatrics . Management of critically ill children with acute necrotizing encephalitis during an H1N1 outbreak in a tertiary pediatric hospital

tetano

Editor, Senior Moderator
Neuropediatrics


. 2024 Oct 17.
doi: 10.1055/a-2442-5810. Online ahead of print. Management of critically ill children with acute necrotizing encephalitis during an H1N1 outbreak in a tertiary pediatric hospital: a series of three cases and literature review

Annalisa Deleuterio[SUP] 1 [/SUP], Paolo Rufini[SUP] 1 [/SUP], Manuela Lerario[SUP] 1 [/SUP], Gabriele Simonini[SUP] 1 [/SUP], Carlotta Montagnani[SUP] 1 [/SUP], Stefano Ermini[SUP] 1 [/SUP], Silvia Ricci[SUP] 1 [/SUP], Luca Bartolini[SUP] 1 [/SUP], Zaccaria Ricci[SUP] 1 [/SUP]



Affiliations
Abstract

Acute necrotizing encephalopathy (ANE) is a severe neurologic condition that is diagnosed clinically and upon specific radiologic imaging. Medical treatment of this condition is uncertain, and timing is likely very important to minimize brain damage and systemic inflammation. The present case series describes three patients suffering from ANE secondary to influenza A/H1N1 infection during a recent outbreak, treated with increasingly aggressive anti-inflammatory approach, and with significantly different outcomes.


 
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