tetano
Editor, Senior Moderator
Neurol Sci
. 2021 Apr 16.
doi: 10.1007/s10072-021-05233-y. Online ahead of print.
Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report
Marco Bozzali[SUP] 1 2 [/SUP], Alberto Grassini[SUP] 3 [/SUP], Giovanni Morana[SUP] 3 [/SUP], Michela Zotta[SUP] 4 [/SUP], Sara Cabras[SUP] 3 [/SUP], Alberto Romagnolo[SUP] 3 [/SUP], Carlo Alberto Artusi[SUP] 3 [/SUP], Elisa Montalenti[SUP] 5 [/SUP], Mario Giorgio Rizzone[SUP] 3 [/SUP], Diego Garbossa[SUP] 3 [/SUP], Elisa Montanaro[SUP] 5 [/SUP], Mara Cercignani[SUP] 6 [/SUP], Leonardo Lopiano[SUP] 3 5 [/SUP]
Affiliations
Abstract
We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic resonance imaging, and 18-FDG positron emission tomography. Beyond the clinical interest, this case contributes to clarify the possible pathways by which SARS-CoV-2 may enter the central nervous system and cause long-term neurological complications.
Keywords: COVID-19; Encephalitis; Epilepsy; Focal seizures with impaired awareness.
. 2021 Apr 16.
doi: 10.1007/s10072-021-05233-y. Online ahead of print.
Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report
Marco Bozzali[SUP] 1 2 [/SUP], Alberto Grassini[SUP] 3 [/SUP], Giovanni Morana[SUP] 3 [/SUP], Michela Zotta[SUP] 4 [/SUP], Sara Cabras[SUP] 3 [/SUP], Alberto Romagnolo[SUP] 3 [/SUP], Carlo Alberto Artusi[SUP] 3 [/SUP], Elisa Montalenti[SUP] 5 [/SUP], Mario Giorgio Rizzone[SUP] 3 [/SUP], Diego Garbossa[SUP] 3 [/SUP], Elisa Montanaro[SUP] 5 [/SUP], Mara Cercignani[SUP] 6 [/SUP], Leonardo Lopiano[SUP] 3 5 [/SUP]
Affiliations
- PMID: 33864172
- DOI: 10.1007/s10072-021-05233-y
Abstract
We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic resonance imaging, and 18-FDG positron emission tomography. Beyond the clinical interest, this case contributes to clarify the possible pathways by which SARS-CoV-2 may enter the central nervous system and cause long-term neurological complications.
Keywords: COVID-19; Encephalitis; Epilepsy; Focal seizures with impaired awareness.