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Netherlands - Atypical BSE variant ('Mad Cow Disease') found in cattle in South Holland

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Atypical BSE variant found in cattle in South Holland

News item | 01-02-2023 | 5:13 pm

A positive case of BSE ('Mad Cow Disease') was found this week in the cadaver of an 8-year-old cow in South Holland. Wageningen Bioveterinary Research (WBVR) has investigated which variant of BSE it concerns. The result of WBVR indicates that this is an atypical variant.

Atypical cases of BSE occur sporadically in older cows, a type of 'old-age BSE'. The last time this occurred in the Netherlands was 2011. Scientists believe that the atypical variants can arise spontaneously. So far, four atypical cases have been identified in the Netherlands.

Minister Piet Adema: It is really shocking when you hear that a cow has tested positive for BSE, because we have not had a BSE case for a long time. I am relieved that this is now the so-called 'atypical variant', so the consequences are mainly limited to the company in question. It is of course very bad for the livestock farmer in question. 13 cattle that are related to this cow because they are descendants or have been raised together will be taken away to be killed and tested. This case has been resolved with these measures. Food safety is not at risk. It is good to note that our monitoring system for BSE does work.

Continuation

The company of the holder of the positive case is immediately blocked. The Dutch Food and Consumer Product Safety Authority (NVWA) has carried out source and contact research in which the offspring of this cow younger than 2 years old are killed and tested. In order to perform BSE tests on brain material, the animal must first be killed.

The NVWA's source and contact investigation showed that the infected bovine had five offspring, one of which is still alive on the same farm. This bovine is less than 2 years old. This one is killed and tested. The remaining four offspring are older than two years, making it unlikely that transmission from mother to these calves could have taken place. They therefore pose no risk to public health.

All cattle born on the same farm as the infected cattle within twelve months before or after the birth of this cattle will also be killed and tested, as well as all cattle that were kept together with this infected cattle in their first year of life. and who, according to the study, received the same potentially contaminated feed during that period.

A total of 13 cattle have been traced, these are being taken away to be killed and tested. As a result, the products of these animals do not enter the food chain and therefore pose no risk to food safety.

The measures will be implemented as soon as possible.


What is BSE?

BSE (Bovine Spongiform Encephalopathy (BSE)) is a fatal disease that occurs in cattle affecting the central nervous system. It is also a zoonosis that can cause the deadly brain disease variant Creutzfeldt-Jacob in humans. Infection can occur through consumption of infected cattle. There is therefore a European monitoring program in which all cadavers in certain risk groups are tested for the presence of BSE.The bovine that has now been found positive has been traced through this active surveillance.

There are two variants: the atypical variant, which is now the case, and the 'classic variant', which led to the BSE crisis in Europe in the 1980s. Reuse of animal proteins in animal feed was an important cause of the spread of classical BSE. This was followed by a ban on the use of certain types of processed animal proteins in animal feed for cattle.

Documents

https://www.rijksoverheid.nl/actuee...ant-bse-aangetroffen-bij-rund-in-zuid-holland
 
Netherlands - Bovine spongiform encephalopathy - Immediate notification

GENERAL INFORMATION
COUNTRY/TERRITORY OR ZONE
COUNTRY/TERRITORY

ANIMAL TYPE
TERRESTRIAL

DISEASE CATEGORY
OIE-listed

EVENT ID
4876

DISEASE
Bovine spongiform encephalopathy

CAUSAL AGENT
Bovine spongiform encephalopathy prion, atypical strain, L-type

GENOTYPE / SEROTYPE / SUBTYPE
-

START DATE
2023/02/01

REASON FOR NOTIFICATION
Recurrence of an eradicated disease

DATE OF LAST OCCURRENCE
2011/01/11

CONFIRMATION DATE
2023/02/01

EVENT STATUS
On-going

END DATE
-

SELF-DECLARATION
NO

REPORT INFORMATION
REPORT NUMBER
Immediate notification

REPORT ID
IN_159092

REPORT REFERENCE
NL-BSE 2023-1

REPORT DATE
2023/02/02

REPORT STATUS
Validated

NO EVOLUTION REPORT
-

EPIDEMIOLOGY
SOURCE OF EVENT OR ORIGIN OF INFECTION
Unknown or inconclusive

EPIDEMIOLOGICAL COMMENTS

Results from TeSeE Western Blot test and Histology/ PrPSC Immunohistochemical test at the National Reference Laboratory Wageningen Bioveterinary Research (WBVR) confirmed the animal positive for atypical BSE of the L-type on the 1st of February 2023. The animal which was born on 5 October 2014 was killed on the holding with clinical signs of disease not related to BSE. As part of the Dutch targeted BSE surveillance system, the 8 year old cow was tested as fallen stock at the NRL WBVR with positive result of TeSeE SAP Combi Kit ELISA (BioRad) test. The animal's carcass was destroyed. The identified animal did not enter food supply channels and so at no time did it present any risk to human health. Epidemiological investigations are ongoing (socalled feedcohort/birthcohort and offspring within 2 years).

QUANTITATIVE DATA SUMMARY
MEASURING UNIT
Animal

SpeciesSusceptibleCasesDeathsKilled and Disposed ofSlaughtered/ Killed for commercial useVaccinated
Cattle (DOMESTIC)NEW 91 1 0 1 0 0
TOTAL 91 1 0 1 0 0
DIAGNOSTIC DETAILS
CLINICAL SIGNS
YES
...

NEW OUTBREAKS

OB_113294 - ZUID BEIJERLAND
OUTBREAK REFERENCE
-

START DATE
2023/02/01

END DATE
-

DETAILED CHARACTERISATION
-

FIRST ADMINISTRATIVE DIVISION
Zuid-Holland

SECOND ADMINISTRATIVE DIVISION
Korendijk

THIRD ADMINISTRATIVE DIVISION
-

EPIDEMIOLOGICAL UNIT
Farm

LOCATION
Zuid Beijerland

Latitude, Longitude
51.76 , 4.36

OUTBREAKS IN CLUSTER
-

MEASURING UNIT
Animal

AFFECTED POPULATION DESCRIPTION
-

SpeciesSusceptibleCasesDeathsKilled and Disposed ofSlaughtered/ Killed for commercial useVaccinated
Cattle (DOMESTIC)NEW91 1 0 1 0 0
TOTAL 91 1 0 1 0 0
...
https://wahis.woah.org/#/in-review/4876
 
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