tetano
Editor, Senior Moderator
Can J Vet Res. 2013 Oct;77(4):309-313.
Needle-free delivery of an inactivated avian influenza H5N3 virus vaccine elicits potent antibody responses in chickens.
Ogunremi O, Pasick J, Berhane Y.
Source
Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, 3851 Fallowfield Road, Ottawa, Ontario K2H 8P9 (Ogunremi); National Centre for Foreign Animal Diseases, Canadian Food Inspection Agency, Winnipeg, 1015 Arlington Street, Winnipeg, Manitoba R3E 3M4 (Pasick, Berhane).
Abstract
in English, French
A needle-free delivery system was assessed as a route for providing quick, safe, and effective vaccination against avian influenza (AI). Two groups of chickens were vaccinated with a commercially available inactivated H5N3 virus vaccine delivered either with a needle-free device or with the conventional syringe-and-needle method recommended by the vaccine manufacturer. The kinetic aspects of seroconversion, peak antibody levels, and antibody titers were measured by a combination of an indirect enzyme-linked immunosorbent assay and the hemagglutination-inhibition test and were all found to be similar in the 2 groups of chickens. We conclude that the needle-free delivery system could result in effective immunization against H5N1 AI epidemics and pandemics in chickens.
PMID:
24124275
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24124275
Needle-free delivery of an inactivated avian influenza H5N3 virus vaccine elicits potent antibody responses in chickens.
Ogunremi O, Pasick J, Berhane Y.
Source
Ottawa Laboratory Fallowfield, Canadian Food Inspection Agency, 3851 Fallowfield Road, Ottawa, Ontario K2H 8P9 (Ogunremi); National Centre for Foreign Animal Diseases, Canadian Food Inspection Agency, Winnipeg, 1015 Arlington Street, Winnipeg, Manitoba R3E 3M4 (Pasick, Berhane).
Abstract
in English, French
A needle-free delivery system was assessed as a route for providing quick, safe, and effective vaccination against avian influenza (AI). Two groups of chickens were vaccinated with a commercially available inactivated H5N3 virus vaccine delivered either with a needle-free device or with the conventional syringe-and-needle method recommended by the vaccine manufacturer. The kinetic aspects of seroconversion, peak antibody levels, and antibody titers were measured by a combination of an indirect enzyme-linked immunosorbent assay and the hemagglutination-inhibition test and were all found to be similar in the 2 groups of chickens. We conclude that the needle-free delivery system could result in effective immunization against H5N1 AI epidemics and pandemics in chickens.
PMID:
24124275
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/24124275