tetano
Editor, Senior Moderator
Nat Med
. 2020 Nov 30.
doi: 10.1038/s41591-020-01178-5. Online ahead of print.
Effective control of SARS-CoV-2 transmission in Wanzhou, China
Qiuling Shi[SUP] 1 2 [/SUP], Yaoyue Hu[SUP] 1 [/SUP], Bin Peng[SUP] 1 [/SUP], Xiao-Jun Tang[SUP] 1 [/SUP], Wei Wang[SUP] 1 [/SUP], Kun Su[SUP] 3 [/SUP], Chao Luo[SUP] 4 [/SUP], Bo Wu[SUP] 4 [/SUP], Fan Zhang[SUP] 1 [/SUP], Yong Zhang[SUP] 1 [/SUP], Benjamin Anderson[SUP] 5 [/SUP], Xiao-Ni Zhong[SUP] 1 [/SUP], Jing-Fu Qiu[SUP] 6 [/SUP], Cheng Yong Yang[SUP] 7 [/SUP], Ai-Long Huang[SUP] 8 [/SUP]
Affiliations
Abstract
The effectiveness of control measures to contain coronavirus disease 2019 (COVID-19) in Wanzhou, China was assessed. Epidemiological data were analyzed for 183 confirmed COVID-19 cases and their close contacts from five generations of transmission of severe acute respiratory syndrome coronavirus 2 throughout the entire COVID-19 outbreak in Wanzhou. Approximately 67.2% and 32.8% of cases were symptomatic and asymptomatic, respectively. Asymptomatic and presymptomatic transmission accounted for 75.9% of the total recorded transmission. The reproductive number was 1.64 (95% confidence interval: 1.16-2.40) for G1-to-G2 transmission, decreasing to 0.31-0.39 in later generations, concomitant with implementation of rigorous control measures. Substantially higher infection risk was associated with contact within 5 d after the infectors had been infected, frequent contact and ≥8 h of contact duration. The spread of COVID-19 was effectively controlled in Wanzhou by breaking the transmission chain through social distancing, extensive contact tracing, mass testing and strict quarantine of close contacts.
. 2020 Nov 30.
doi: 10.1038/s41591-020-01178-5. Online ahead of print.
Effective control of SARS-CoV-2 transmission in Wanzhou, China
Qiuling Shi[SUP] 1 2 [/SUP], Yaoyue Hu[SUP] 1 [/SUP], Bin Peng[SUP] 1 [/SUP], Xiao-Jun Tang[SUP] 1 [/SUP], Wei Wang[SUP] 1 [/SUP], Kun Su[SUP] 3 [/SUP], Chao Luo[SUP] 4 [/SUP], Bo Wu[SUP] 4 [/SUP], Fan Zhang[SUP] 1 [/SUP], Yong Zhang[SUP] 1 [/SUP], Benjamin Anderson[SUP] 5 [/SUP], Xiao-Ni Zhong[SUP] 1 [/SUP], Jing-Fu Qiu[SUP] 6 [/SUP], Cheng Yong Yang[SUP] 7 [/SUP], Ai-Long Huang[SUP] 8 [/SUP]
Affiliations
- PMID: 33257893
- DOI: 10.1038/s41591-020-01178-5
Abstract
The effectiveness of control measures to contain coronavirus disease 2019 (COVID-19) in Wanzhou, China was assessed. Epidemiological data were analyzed for 183 confirmed COVID-19 cases and their close contacts from five generations of transmission of severe acute respiratory syndrome coronavirus 2 throughout the entire COVID-19 outbreak in Wanzhou. Approximately 67.2% and 32.8% of cases were symptomatic and asymptomatic, respectively. Asymptomatic and presymptomatic transmission accounted for 75.9% of the total recorded transmission. The reproductive number was 1.64 (95% confidence interval: 1.16-2.40) for G1-to-G2 transmission, decreasing to 0.31-0.39 in later generations, concomitant with implementation of rigorous control measures. Substantially higher infection risk was associated with contact within 5 d after the infectors had been infected, frequent contact and ≥8 h of contact duration. The spread of COVID-19 was effectively controlled in Wanzhou by breaking the transmission chain through social distancing, extensive contact tracing, mass testing and strict quarantine of close contacts.