N Engl J Med . Inactivation of Avian Influenza A(H5N1) Virus in Raw Milk at 63°C and 72°C

[tetano]

N Engl J Med


. 2024 Jun 14.
doi: 10.1056/NEJMc2405488. Online ahead of print. Inactivation of Avian Influenza A(H5N1) Virus in Raw Milk at 63°C and 72°C

Franziska Kaiser[SUP] 1 [/SUP], Dylan H Morris[SUP] 2 [/SUP], Arthur Wickenhagen[SUP] 1 [/SUP], Reshma Mukesh[SUP] 1 [/SUP], Shane Gallogly[SUP] 1 [/SUP], Kwe Claude Yinda[SUP] 1 [/SUP], Emmie de Wit[SUP] 1 [/SUP], James O Lloyd-Smith[SUP] 2 [/SUP], Vincent J Munster[SUP] 3 [/SUP]



Affiliations

• PMID: 38875103
• DOI: 10.1056/NEJMc2405488

No abstract available
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[sharon sanders]

snip

"At 72°C, we measured a decrease in infectious virus by a factor of 10[SUP]4[/SUP] within 5 seconds; however, we also detected infectious virus just above the assay limit of detection for as long as 20 seconds at 72°C. This finding indicates the potential for a relatively small but detectable quantity of HPAI A(H5N1) virus to remain infectious in milk after 15 seconds at 72°C if the initial titer is sufficiently high, at least under these specific experimental conditions."​