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Source: https://www.cnn.com/2023/03/30/health/hepatitis-outbreak-adeno-associated-virus/index.html
Mysterious Hepatitis outbreak in kids in 2022 linked to common childhood respiratory virus, studies suggest
By Janelle Chavez, CNN
Published 2:23 PM EDT, Thu March 30, 2023
CNN —
An outbreak of acute severe, unexplained hepatitis in previously healthy children in 2022 may be linked to adeno-associated virus 2, or AAV2, according to three independent studies published Thursday in the journal Nature.
Between April and July 2022, more than 1,000 children worldwide – at least 350 of them in the United States – were diagnosed with hepatitis, a disease involving liver inflammation, with no known cause. Nearly 50 needed liver transplants, and 22 children died, according to the World Health Organization.
New research suggests that AAV2 might be implicated in the disease. This common childhood virus cannot copy itself unless in the presence of another “helper” virus, such as adenovirus or herpesvirus. AAV2 was present among nearly all of the children with unexplained acute hepatitis, and many were infected with multiple helper viruses, the researchers found..
Mysterious Hepatitis outbreak in kids in 2022 linked to common childhood respiratory virus, studies suggest
By Janelle Chavez, CNN
Published 2:23 PM EDT, Thu March 30, 2023
CNN —
An outbreak of acute severe, unexplained hepatitis in previously healthy children in 2022 may be linked to adeno-associated virus 2, or AAV2, according to three independent studies published Thursday in the journal Nature.
Between April and July 2022, more than 1,000 children worldwide – at least 350 of them in the United States – were diagnosed with hepatitis, a disease involving liver inflammation, with no known cause. Nearly 50 needed liver transplants, and 22 children died, according to the World Health Organization.
New research suggests that AAV2 might be implicated in the disease. This common childhood virus cannot copy itself unless in the presence of another “helper” virus, such as adenovirus or herpesvirus. AAV2 was present among nearly all of the children with unexplained acute hepatitis, and many were infected with multiple helper viruses, the researchers found..