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Moderna announced it is sending a new COVID-19 booster shot into clinic, confirms its current two-shot still works.(Getty Images)
Moderna is weighing a second booster shot to battle back a new coronavirus variant, even as it affirms its current vaccine's activity against newly emerging mutants.
While the current two-dose regimen is holding so far, it's less effective against a South African variant—which has the company exploring a third shot and a variant-specific booster.
The variant candidate is moving into preclinical studies and a phase 1 U.S. study, targeting the coronavirus strain first identified in South Africa, Moderna said Monday.
....In a press release, Moderna stated that its mRNA-1273 COVID-19 vaccine can probably protect people against variants of the disease first found in South Africa and the UK. The current vaccine showed lower levels of antibodies in lab testing against the South African variant, however.
"Out of an abundance of caution," the biotech company will begin testing a booster shot tailored to protect people against the South African variant, according to Moderna CEO St?phane Bancel.
"We continue to believe the emerging variants represent a management challenge that was anticipated when developing a vaccine against a coronavirus," said analysts from Morgan Stanley. "Overall, we are encouraged that mRNA-1273 is expected to protect against severe disease, which remains a major issue driving hospitalization rates. We remain focused on the durability of protection, rate/prevalence of emerging variants and a validated surrogate of protection." ....:tiphat:https://www.businessinsider.com/mod...ns-coronavirus-vaccine-south-africa-uk-2021-1
