tetano
Editor, Senior Moderator
Microbiol Immunol
. 2022 Jan 10.
doi: 10.1111/1348-0421.12962. Online ahead of print.
Viral shedding and the durability of IgG antibodies to SARS-CoV-2
Maria Inge Lusida[SUP] 1 [/SUP], Emily Gunawan[SUP] 1 [/SUP], Ni Luh Ayu Megasari[SUP] 1 [/SUP], Laura Navika Yamani[SUP] 1 2 [/SUP], Juniastuti[SUP] 1 [/SUP], Takako Utsumi[SUP] 1 3 [/SUP], Yasuko Mori[SUP] 3 [/SUP]
Affiliations
Abstract
We followed 45 participants in Surabaya, Indonesia, for 10 months and compared their polymerase chain reaction (PCR) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) results. Thirteen out of 45 participants were IgG seropositive at least once while the remaining 32 stayed IgG seronegative throughout the study. Among 13 seropositive participants, 9 participants were consecutively seropositive at least twice and were eligible for IgG longevity evaluation. The duration of IgG detection varied from 47 to ≥ 233 days. We observed intermittent re-positive PCR results suggestive of viral shedding in subjects with a longer duration of IgG detection. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; Immunoglobulin G; Indonesia; SARS-CoV-2.
. 2022 Jan 10.
doi: 10.1111/1348-0421.12962. Online ahead of print.
Viral shedding and the durability of IgG antibodies to SARS-CoV-2
Maria Inge Lusida[SUP] 1 [/SUP], Emily Gunawan[SUP] 1 [/SUP], Ni Luh Ayu Megasari[SUP] 1 [/SUP], Laura Navika Yamani[SUP] 1 2 [/SUP], Juniastuti[SUP] 1 [/SUP], Takako Utsumi[SUP] 1 3 [/SUP], Yasuko Mori[SUP] 3 [/SUP]
Affiliations
- PMID: 35007349
- DOI: 10.1111/1348-0421.12962
Abstract
We followed 45 participants in Surabaya, Indonesia, for 10 months and compared their polymerase chain reaction (PCR) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) results. Thirteen out of 45 participants were IgG seropositive at least once while the remaining 32 stayed IgG seronegative throughout the study. Among 13 seropositive participants, 9 participants were consecutively seropositive at least twice and were eligible for IgG longevity evaluation. The duration of IgG detection varied from 47 to ≥ 233 days. We observed intermittent re-positive PCR results suggestive of viral shedding in subjects with a longer duration of IgG detection. This article is protected by copyright. All rights reserved.
Keywords: COVID-19; Immunoglobulin G; Indonesia; SARS-CoV-2.