tetano
Editor, Senior Moderator
Med Hypotheses
. 2020 Jun 2;144:109946.
doi: 10.1016/j.mehy.2020.109946. Online ahead of print.
Could Nutritional and Functional Status Serve as Prognostic Factors for COVID-19 in the Elderly?
Irene Lidoriki[SUP] 1 [/SUP], Maximos Frountzas[SUP] 2 [/SUP], Dimitrios Schizas[SUP] 1 [/SUP]
Affiliations
Abstract
Geriatric patients seem to be the most vulnerable group in COVID-19. These patients are usually characterized by impaired mobilization and malnutrition. In addition, obesity has been correlated with increased mortality rates after COVID-19 infection, highlighting the role of nutrition in prognosis of COVID-19 as well. In the past, several indices of nutritional status (GNRI) and functional status (ECOG performance status, Barthel Index, Handgrip Strength) have demonstrated a prognostic ability for hospitalized patients with influenza-like respiratory infections from coronavirus, metapneumovirus, parainfluenza and rhinovirus. Our hypothesis suggests that the previously mentioned nutritional and functional status indices, combined with the pneumonia severity index (CRB-65), could be useful in prognosis of morbidity and mortality of the elderly after the novel COVID-19 infection. Our hypothesis, is the first in the literature, which suggests a prognostic association between nutritional status of patients and COVID-19 infection, offering a quick and low-cost prognostic tool for COVID-19 in the elderly.
Keywords: COVID-19; Elderly; Frailty; Functional status; Malnutrition.
. 2020 Jun 2;144:109946.
doi: 10.1016/j.mehy.2020.109946. Online ahead of print.
Could Nutritional and Functional Status Serve as Prognostic Factors for COVID-19 in the Elderly?
Irene Lidoriki[SUP] 1 [/SUP], Maximos Frountzas[SUP] 2 [/SUP], Dimitrios Schizas[SUP] 1 [/SUP]
Affiliations
- PMID: 32512494
- PMCID: PMC7264929
- DOI: 10.1016/j.mehy.2020.109946
Abstract
Geriatric patients seem to be the most vulnerable group in COVID-19. These patients are usually characterized by impaired mobilization and malnutrition. In addition, obesity has been correlated with increased mortality rates after COVID-19 infection, highlighting the role of nutrition in prognosis of COVID-19 as well. In the past, several indices of nutritional status (GNRI) and functional status (ECOG performance status, Barthel Index, Handgrip Strength) have demonstrated a prognostic ability for hospitalized patients with influenza-like respiratory infections from coronavirus, metapneumovirus, parainfluenza and rhinovirus. Our hypothesis suggests that the previously mentioned nutritional and functional status indices, combined with the pneumonia severity index (CRB-65), could be useful in prognosis of morbidity and mortality of the elderly after the novel COVID-19 infection. Our hypothesis, is the first in the literature, which suggests a prognostic association between nutritional status of patients and COVID-19 infection, offering a quick and low-cost prognostic tool for COVID-19 in the elderly.
Keywords: COVID-19; Elderly; Frailty; Functional status; Malnutrition.