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mBio . The value of observational registry studies for the next infectious disease emergency

tetano

Editor, Senior Moderator
mBio


. 2023 Nov 8:e0256523.
doi: 10.1128/mbio.02565-23. Online ahead of print. The value of observational registry studies for the next infectious disease emergency

Jonathon W Senefeld[SUP] 1 [/SUP], Peter Marks[SUP] 2 [/SUP], Arturo Casadevall[SUP] 3 [/SUP], Michael J Joyner[SUP] 4 [/SUP]



Affiliations
Abstract

During infectious disease emergencies, it may be necessary to deploy new therapies without conclusive evidence for their effectiveness. During the SARS-CoV-2 pandemic, several countries used registries to track the use of COVID-19 convalescent plasma (CCP). Those registries provided evidence that CCP was effective when used early and with high titer.

Keywords: clinical trials; coronavirus; neutralizing antibodies.

 
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