Gert van der Hoek
In Memoriam - Editor, Senior Moderator
Emerg Infect Dis. 2016 Apr; 22(4): 657–663.
doi: 10.3201/eid2204.151814
Lassa Virus Seroprevalence in Sibirilia Commune, Bougouni District, Southern Mali
Lassa virus (LASV) is endemic to several nations in West Africa. In Mali, LASV was unknown until an exported case of Lassa fever was reported in 2009. Since that time, rodent surveys have found evidence of LASV-infected Mastomys natalensis rats in several communities in southern Mali, near the border with C?te d’Ivoire. Despite increased awareness, to date only a single case of Lassa fever has been confirmed in Mali.
We conducted a survey to determine the prevalence of LASV exposure among persons in 3 villages in southern Mali where the presence of infected rodents has been documented. LASV IgG seroprevalence ranged from 14.5% to 44% per village. No sex bias was noted; however, seropositivity rates increased with participant age. These findings confirm human LASV exposure in Mali and suggest that LASV infection/Lassa fever is a potential public health concern in southern Mali.
LINK TO FULL ARTICLE
doi: 10.3201/eid2204.151814
PMCID: PMC4806955
Lassa Virus Seroprevalence in Sibirilia Commune, Bougouni District, Southern Mali
Lassa virus (LASV) is endemic to several nations in West Africa. In Mali, LASV was unknown until an exported case of Lassa fever was reported in 2009. Since that time, rodent surveys have found evidence of LASV-infected Mastomys natalensis rats in several communities in southern Mali, near the border with C?te d’Ivoire. Despite increased awareness, to date only a single case of Lassa fever has been confirmed in Mali.
We conducted a survey to determine the prevalence of LASV exposure among persons in 3 villages in southern Mali where the presence of infected rodents has been documented. LASV IgG seroprevalence ranged from 14.5% to 44% per village. No sex bias was noted; however, seropositivity rates increased with participant age. These findings confirm human LASV exposure in Mali and suggest that LASV infection/Lassa fever is a potential public health concern in southern Mali.
LINK TO FULL ARTICLE