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Long-term effect of melamine on humans is still unknown; Study shows WHO TDI for infants too high

Emily

Editor, Senior Moderator
http://tih.sagepub.com/content/early/2011/10/08/0748233711416950.abstract
Review of melamine scandal: still a long way ahead
Yuejiao Wei
Key Laboratory of Animal Resistance, College of Life Science, Shandong Normal University, Jinan, China


http://www.nature.com/ki/journal/v80/n7/abs/ki2011174a.html
Kidney International (2011) 80, 694?696; doi:10.1038/ki.2011.174
Melamine toxicity: one more culprit in calcium kidney lithiasis


http://www.tandfonline.com/doi/abs/10.1080/19440049.2010.548083
Food Additives & Contaminants: Part A
Volume 28, Issue 4, 2011
Available online: 18 Feb 2011
A hierarchical Bayesian approach for risk assessment of melamine in infant formula based on cases of related nephrolithiasis in children
[snip]
Based on the background exposure, spontaneous rate, and mode of action (MOA) of nephrolithiasis in children, the simulated lower bounds of the 95% CIs daily melamine intake ranged from 0.008 to 0.03 mg/kg BW/day corresponding to an additional risks of 0.1% is proposed as a plausible TDI, which is approximately an order lower than the current WHO-suggested TDI level of 0.2 mg/kg BW/day. More stringent regulations on melamine levels in infant formula should be considered to protect young children fully.

http://tau.sagepub.com/content/3/1/3.short
Therapeutic Advances in Urology February 2011 vol. 3 no. 1 3-12
The increasing pediatric stone disease problem
Douglass B. Clayton
Vanderbilt University Medical Center, Department of Urologic Surgery, Division of Pediatric Urology, Nashville, TN, USA

http://www.sciencedirect.com/science/article/pii/S0378427411014949
Toxicology Letters
Volume 206, Issue 3, 30 October 2011, Pages 276-280
Cognitive deficits induced by melamine in rats
 
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