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Source: http://7thspace.com/headlines/43116...iv_strains_in_clinical_cases_from_kerala.html
Lineage shift in Indian strains of Dengue virus serotype-3 (Genotype III), evidenced by detection of lineage IV strains in clinical cases from Kerala
Local epidemiology of Dengue is defined by the genetic diversity of the circulating Dengue virus (DENV) strains. This important information is not available for the virus strains from most parts of the Indian subcontinent.
The present study focused on the genetic diversity of the serotype 3 DENV strains (DENV-3) from India...
... Conclusions: Our study identifies for the first time the presence of lineage IV strains in the Indian subcontinent.
Results indicate the possibility of a recent exotic introduction and also a shift from the existing lineage III strains to lineage IV. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world.
Hence the present observation could be significant in terms of the clinical severity of future dengue cases in the region.
Author: Anoop ManakkadanIype JosephRaji Rajendran PrasannaRiaz Ismail kunjuLalitha KailasEaswaran Sreekumar
Credits/Source: Virology Journal 2013, 10:37
Published on: 2013-01-29
Lineage shift in Indian strains of Dengue virus serotype-3 (Genotype III), evidenced by detection of lineage IV strains in clinical cases from Kerala
Local epidemiology of Dengue is defined by the genetic diversity of the circulating Dengue virus (DENV) strains. This important information is not available for the virus strains from most parts of the Indian subcontinent.
The present study focused on the genetic diversity of the serotype 3 DENV strains (DENV-3) from India...
... Conclusions: Our study identifies for the first time the presence of lineage IV strains in the Indian subcontinent.
Results indicate the possibility of a recent exotic introduction and also a shift from the existing lineage III strains to lineage IV. Lineage shifts in DENV-3 strains have been attributed to dramatic increase in disease severity in many parts of the world.
Hence the present observation could be significant in terms of the clinical severity of future dengue cases in the region.
Author: Anoop ManakkadanIype JosephRaji Rajendran PrasannaRiaz Ismail kunjuLalitha KailasEaswaran Sreekumar
Credits/Source: Virology Journal 2013, 10:37
Published on: 2013-01-29