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Lancet ID: The eyes have it: influenza virus infection beyond the respiratory tract

tetano

Editor, Senior Moderator
Lancet Infect Dis. 2018 Feb 21. pii: S1473-3099(18)30102-6. doi: 10.1016/S1473-3099(18)30102-6. [Epub ahead of print]
[h=1]The eyes have it: influenza virus infection beyond the respiratory tract.[/h] Belser JA[SUP]1[/SUP], Lash RR[SUP]2[/SUP], Garg S[SUP]3[/SUP], Tumpey TM[SUP]3[/SUP], Maines TR[SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] Avian and human influenza A viruses alike have shown a capacity to use the eye as a portal of entry and cause ocular disease in human beings. However, whereas influenza viruses generally represent a respiratory pathogen and only occasionally cause ocular complications, the H7 virus subtype stands alone in possessing an ocular tropism. Clarifying what confers such non-respiratory tropism to a respiratory virus will permit a greater ability to identify, treat, and prevent zoonotic human infection following ocular exposure to influenza viruses; especially those within the H7 subtype, which continue to cause avian epidemics on many continents.


PMID: 29477464 DOI: 10.1016/S1473-3099(18)30102-6
 
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