tetano
Editor, Senior Moderator
Acta Neurol Scand. 2012 May 10. doi: 10.1111/j.1600-0404.2012.01675.x. [Epub ahead of print]
Lambert-Eaton myasthenic syndrome following H1N1-influenza vaccination - a case report.
Ansakorpi H, Rusanen H, Rytky S, F?rkkil? M.
Source
Department of Neurology, Oulu University Hospital, Oulu, Finland.
Abstract
BACKGROUND:
The outbreak of influenza A (H1N1) pandemic during the year 2009 led to the development of several vaccinations against H1N1 virus. In Finland, 2.6 million citizens were vaccinated during pandemic 2009 - 2010 with adjuvanted influenza vaccine, Pandemrix(?) .
CLINICAL PRESENTATION:
In this case report, we describe a patient with non-paraneoplastic Lambert-Eaton myasthenic syndrome following Pandemrix(?) vaccination.
CONCLUSION:
Development of various autoimmune diseases in genetically predisposed subjects following exposure to certain environmental factors, including vaccinations, is a well-known entity. Clinicians should be aware of the possibility of the induction of autoimmune diseases following vaccinations and actively ask the relevant clinical history in a newly diagnosed patient with an autoimmune disorder.
? 2012 John Wiley & Sons A/S.
PMID:
22571392
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22571392
Lambert-Eaton myasthenic syndrome following H1N1-influenza vaccination - a case report.
Ansakorpi H, Rusanen H, Rytky S, F?rkkil? M.
Source
Department of Neurology, Oulu University Hospital, Oulu, Finland.
Abstract
BACKGROUND:
The outbreak of influenza A (H1N1) pandemic during the year 2009 led to the development of several vaccinations against H1N1 virus. In Finland, 2.6 million citizens were vaccinated during pandemic 2009 - 2010 with adjuvanted influenza vaccine, Pandemrix(?) .
CLINICAL PRESENTATION:
In this case report, we describe a patient with non-paraneoplastic Lambert-Eaton myasthenic syndrome following Pandemrix(?) vaccination.
CONCLUSION:
Development of various autoimmune diseases in genetically predisposed subjects following exposure to certain environmental factors, including vaccinations, is a well-known entity. Clinicians should be aware of the possibility of the induction of autoimmune diseases following vaccinations and actively ask the relevant clinical history in a newly diagnosed patient with an autoimmune disorder.
? 2012 John Wiley & Sons A/S.
PMID:
22571392
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/22571392