tetano
Editor, Senior Moderator
[h=1]Presence of Zika Virus in Conjunctival Fluid FREE ONLINE FIRST[/h] Jiufeng Sun, PhD[SUP]1[/SUP]; De Wu, PhD[SUP]2[/SUP]; Haojie Zhong[SUP]2[/SUP]; Dawei Guan[SUP]2[/SUP]; Huan Zhang[SUP]2[/SUP]; Qiqi Tan[SUP]2[/SUP]; Changwen Ke, PhD[SUP]2[/SUP]
[+] Author Affiliations
JAMA Ophthalmol. Published online September 15, 2016. doi:10.1001/jamaophthalmol.2016.3417
Zika virus (ZIKV) is a mosquito-borne flavivirus isolated from the Zika forest of Uganda in 1947.[SUP]1[/SUP] The clinical symptoms of ZIKV infection are mostly a mild and self-limited rash, arthralgia, and conjunctivitis in humans. More than 80% of ZIKV infections are asymptomatic. The ZIKV outbreaks in Brazil and French Polynesia indicate that the virus is linked to microcephaly and Guillain-Barr? syndrome.[SUP]2[/SUP][SUP],3[/SUP] Meanwhile, severe eye damage in infants with microcephaly was associated with ZIKV infection.[SUP]4[/SUP] However, it is still unclear whether the eye lesions are the result of microcephaly or directly ZIKV infection.[SUP]5[/SUP] Therefore, we wondered whether ZIKV could be detected in conjunctival fluid. In this report, we describe the detection of ZIKV from conjunctival swab samples of laboratory-confirmed ZIKV cases.
full article
https://archopht.jamanetwork.com/article.aspx?articleid=2552685
[+] Author Affiliations
JAMA Ophthalmol. Published online September 15, 2016. doi:10.1001/jamaophthalmol.2016.3417
Zika virus (ZIKV) is a mosquito-borne flavivirus isolated from the Zika forest of Uganda in 1947.[SUP]1[/SUP] The clinical symptoms of ZIKV infection are mostly a mild and self-limited rash, arthralgia, and conjunctivitis in humans. More than 80% of ZIKV infections are asymptomatic. The ZIKV outbreaks in Brazil and French Polynesia indicate that the virus is linked to microcephaly and Guillain-Barr? syndrome.[SUP]2[/SUP][SUP],3[/SUP] Meanwhile, severe eye damage in infants with microcephaly was associated with ZIKV infection.[SUP]4[/SUP] However, it is still unclear whether the eye lesions are the result of microcephaly or directly ZIKV infection.[SUP]5[/SUP] Therefore, we wondered whether ZIKV could be detected in conjunctival fluid. In this report, we describe the detection of ZIKV from conjunctival swab samples of laboratory-confirmed ZIKV cases.
full article
https://archopht.jamanetwork.com/article.aspx?articleid=2552685