tetano
Editor, Senior Moderator
J Pharm Bioallied Sci
. 2022 Apr-Jun;14(2):81-92.
doi: 10.4103/jpbs.jpbs_460_21. Epub 2022 Jul 18.
Scoping Review of Six Retrospective Studies: Risk Factors Associated With the Case Fatality Rate of People Infected With Coronavirus (COVID-19)
Adel Sadeq[SUP] 1 [/SUP], Asim Ahmed Elnour[SUP] 2 3 [/SUP], Farah Hamad Farah[SUP] 4 5 [/SUP], Azza Ramadan[SUP] 6 [/SUP], Judit Don[SUP] 7 [/SUP], Ahmed Ibrahim Fathelrahman[SUP] 8 [/SUP], Maisoun Alkaabi[SUP] 9 [/SUP], Mohammed Baraka[SUP] 10 11 [/SUP], Abubakar B Abubakar[SUP] 12 [/SUP], Sasha Mohammed Elamin Suliman[SUP] 13 [/SUP], Abdulla Al Amoodi[SUP] 14 [/SUP], IsraaYousif Khidir[SUP] 15 [/SUP], Khalid Awad Al Kubaisi[SUP] 16 [/SUP], Nadia Al Mazroui[SUP] 17 [/SUP]
Affiliations
Abstract
Background: It would be rational to describe the pattern of the clinical characteristics of the survivors and the nonsurvivors during the critical intensive-infection era of coronavirus disease 2019 (COVID-19). The explicit objective of the current scoping review was to delineate the predictive risk factors associated with case fatality rate (CFR).
Methods: Six retrospective studies of subjects infected with COVID-19 published between December 1, 2020, and March 30, 2020, describing nonsurvivors in Wuhan/Hubei, China, were identified.
Results: There were 1769 subjects with a mean age of 52 years, and 65.9% were male. The highest comorbidity reported was cardiovascular diseases at 22.2% (393/1769). The overall number of cases admitted to the intensive care unit was 228 (12.9%). The reported overall CFR was 7.7% (136/1769), with the highest at 28.2% (54/191), and the lowest at 1.4% (15/1099). The mean duration of onset until death for nonsurvivors was 15.3 days.
Conclusion: We have found that older age, male gender, the longer duration from onset till death (days), development of acute respiratory distress syndrome/shock, preexisting diabetes, and preexisting cardiovascular diseases were the major risk factors associated with high CFR.
Keywords: Case fatality rate; coronavirus disease 2019; nonsurvivors; predictive risk factors; survivors.
. 2022 Apr-Jun;14(2):81-92.
doi: 10.4103/jpbs.jpbs_460_21. Epub 2022 Jul 18.
Scoping Review of Six Retrospective Studies: Risk Factors Associated With the Case Fatality Rate of People Infected With Coronavirus (COVID-19)
Adel Sadeq[SUP] 1 [/SUP], Asim Ahmed Elnour[SUP] 2 3 [/SUP], Farah Hamad Farah[SUP] 4 5 [/SUP], Azza Ramadan[SUP] 6 [/SUP], Judit Don[SUP] 7 [/SUP], Ahmed Ibrahim Fathelrahman[SUP] 8 [/SUP], Maisoun Alkaabi[SUP] 9 [/SUP], Mohammed Baraka[SUP] 10 11 [/SUP], Abubakar B Abubakar[SUP] 12 [/SUP], Sasha Mohammed Elamin Suliman[SUP] 13 [/SUP], Abdulla Al Amoodi[SUP] 14 [/SUP], IsraaYousif Khidir[SUP] 15 [/SUP], Khalid Awad Al Kubaisi[SUP] 16 [/SUP], Nadia Al Mazroui[SUP] 17 [/SUP]
Affiliations
- PMID: 36034490
- PMCID: PMC9416107
- DOI: 10.4103/jpbs.jpbs_460_21
Abstract
Background: It would be rational to describe the pattern of the clinical characteristics of the survivors and the nonsurvivors during the critical intensive-infection era of coronavirus disease 2019 (COVID-19). The explicit objective of the current scoping review was to delineate the predictive risk factors associated with case fatality rate (CFR).
Methods: Six retrospective studies of subjects infected with COVID-19 published between December 1, 2020, and March 30, 2020, describing nonsurvivors in Wuhan/Hubei, China, were identified.
Results: There were 1769 subjects with a mean age of 52 years, and 65.9% were male. The highest comorbidity reported was cardiovascular diseases at 22.2% (393/1769). The overall number of cases admitted to the intensive care unit was 228 (12.9%). The reported overall CFR was 7.7% (136/1769), with the highest at 28.2% (54/191), and the lowest at 1.4% (15/1099). The mean duration of onset until death for nonsurvivors was 15.3 days.
Conclusion: We have found that older age, male gender, the longer duration from onset till death (days), development of acute respiratory distress syndrome/shock, preexisting diabetes, and preexisting cardiovascular diseases were the major risk factors associated with high CFR.
Keywords: Case fatality rate; coronavirus disease 2019; nonsurvivors; predictive risk factors; survivors.