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J Med Virol. 2019 novel coronavirus patients' clinical characteristics, discharge rate and fatality rate of meta-analysis

tetano

Editor, Senior Moderator
J Med Virol. 2020 Mar 12. doi: 10.1002/jmv.25757. [Epub ahead of print] [h=1]2019 novel coronavirus patients' clinical characteristics, discharge rate and fatality rate of meta-analysis.[/h]
Li LQ[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Huang T[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Wang YQ[SUP]4[/SUP], Wang ZP[SUP]5[/SUP], Liang Y[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Huang TB[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Zhang HY[SUP]1,[/SUP][SUP]2,[/SUP][SUP]3[/SUP], Sun WM[SUP]6[/SUP], Wang YP[SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] To study the clinical data, discharge rate, and fatality rate of COVID-19 patients for clinical help.
[h=4]METHODS:[/h] The clinical data of COVID-19 patients from December 2019 to February 2020 were retrieved from four databases. We statistically analyzed the clinical symptoms and laboratory results of COVID-19 patients and explained the discharge rate, fatality rate with a single-arm meta-analysis.
[h=4]RESULTS:[/h] The available data of 1994 patients in 10 literatures were included in our study. The main clinical symptoms of COVID-19 patients were fever (88.5%), cough (68.6%), myalgia or fatigue (35.8%), expectoration (28.2%), dyspnea (21.9%). Minor symptoms include headache or dizziness: (12.1%) diarrhea (4.8%), nausea, and vomiting (3.9%). The results of laboratory results showed that the lymphocytopenia (64.5%), increase of CRP (44.3%), increase of LDH (28.3%), and leukocytopenia (29.4%) were more common.
[h=4]CONCLUSIONS:[/h] The results of single-arm meta-analysis showed that: the male took a larger percentage in the gender distribution of COVID-19 patients 60%[95%CI (0.54,0.65)], the discharge rate of COVID-19 patients was 42%[95%CI (0.29,0.55)], and the fatality rate was 7%[95%CI (0.04,0.10)]. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.


[h=4]KEYWORDS:[/h] 2019-nCoV; COVID-19; clinical characteristics; discharge rate; fatality rate; meta-analysis

PMID: 32162702 DOI: 10.1002/jmv.25757
 
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