tetano
Editor, Senior Moderator
J Korean Med Sci
. 2022 Feb 28;37(8):e67.
doi: 10.3346/jkms.2022.37.e67.
Kinetics of Neutralizing Antibody Responses Against SARS-CoV-2 Delta Variant in Patients Infected at the Beginning of the Pandemic
Pyoeng Gyun Choe[SUP] #[/SUP][SUP] 1 [/SUP], Yuri Kim[SUP] #[/SUP][SUP] 2 [/SUP], Euijin Chang[SUP] 1 [/SUP], Chang Kyung Kang[SUP] 1 [/SUP], Nam Joong Kim[SUP] 1 [/SUP], Nam-Hyuk Cho[SUP] 3 [/SUP], Wan Beom Park[SUP] 4 [/SUP], Myoung-Don Oh[SUP] 1 [/SUP]
Affiliations
Abstract
We investigated the kinetics of the neutralizing antibody responses to the severe acute respiratory syndrome-coronavirus-2 delta variant over the course of 1 year in 16 patients infected at the beginning of the pandemic. In patients with severe disease, neutralizing responses to the delta variant were detectable, albeit at lower levels than responses to the wild type. Neutralizing responses to the delta variant were undetectable, however, in asymptomatic persons. This finding implies that the vaccination strategy for persons with past natural infection should depend on the severity of the previous infection.
Keywords: COVID-19; Delta Variant; FRNT; SARS-CoV-2.
. 2022 Feb 28;37(8):e67.
doi: 10.3346/jkms.2022.37.e67.
Kinetics of Neutralizing Antibody Responses Against SARS-CoV-2 Delta Variant in Patients Infected at the Beginning of the Pandemic
Pyoeng Gyun Choe[SUP] #[/SUP][SUP] 1 [/SUP], Yuri Kim[SUP] #[/SUP][SUP] 2 [/SUP], Euijin Chang[SUP] 1 [/SUP], Chang Kyung Kang[SUP] 1 [/SUP], Nam Joong Kim[SUP] 1 [/SUP], Nam-Hyuk Cho[SUP] 3 [/SUP], Wan Beom Park[SUP] 4 [/SUP], Myoung-Don Oh[SUP] 1 [/SUP]
Affiliations
- PMID: 35226425
- DOI: 10.3346/jkms.2022.37.e67
Abstract
We investigated the kinetics of the neutralizing antibody responses to the severe acute respiratory syndrome-coronavirus-2 delta variant over the course of 1 year in 16 patients infected at the beginning of the pandemic. In patients with severe disease, neutralizing responses to the delta variant were detectable, albeit at lower levels than responses to the wild type. Neutralizing responses to the delta variant were undetectable, however, in asymptomatic persons. This finding implies that the vaccination strategy for persons with past natural infection should depend on the severity of the previous infection.
Keywords: COVID-19; Delta Variant; FRNT; SARS-CoV-2.