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J Int Med Res . Comparison of the clinical parameters of patients with COVID-19 and influenza using blood test data: a retrospective cross-sectiona

tetano

Editor, Senior Moderator
J Int Med Res


. 2022 Feb;50(2):3000605221083751.
doi: 10.1177/03000605221083751.
Comparison of the clinical parameters of patients with COVID-19 and influenza using blood test data: a retrospective cross-sectional survey


Sayato Fukui[SUP] 1 [/SUP], Akihiro Inui[SUP] 1 [/SUP], Mizue Saita[SUP] 1 [/SUP], Daiki Kobayashi[SUP] 1 2 [/SUP], Toshio Naito[SUP] 1 [/SUP]



Affiliations

Abstract

Objective: The characteristic features, including blood test data, of the novel coronavirus disease 2019 (COVID-19) versus influenza have not been defined. We therefore compared the clinical parameters, including blood test data, of COVID-19 and influenza.
Methods: This retrospective cross-sectional survey was conducted at Juntendo University Nerima Hospital. We recruited patients diagnosed with COVID-19 between 1 January 2020 and 31 December 2020 who underwent blood tests. For comparison, we recruited an equivalent number of patients who were diagnosed with influenza and who underwent blood tests.
Results: During the study period, 228 patients (male:female, 123 [54.0%]:105 [46.0%]; age, 54.68 ± 18.98 years) were diagnosed with COVID-19. We also recruited 228 patients with influenza (male:female, 129 [56.6%]:99 [43.4%]; age, 69.6 ± 21.25 years). An age of 15 to 70 years (vs. 71 years), breathing difficulty, and malaise were significantly more common in patients with COVID-19 than in those with influenza. However, nausea, body temperature >38.1°C, and white blood cell count >9000/μL were more common in patients with influenza.
Conclusions: Our results are useful for differentiating COVID-19 from influenza, and these findings will be extremely helpful for future practice as we learn to coexist with COVID-19.

Keywords: Clinical feature; blood testing; breathing difficulty; coronavirus disease 2019; influenza; leukocytosis; malaise; nausea; severe acute respiratory syndrome coronavirus-2.
 
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