Giuseppe
Emeritus
[Source: Journal of Infectious Diseases, full page: (LINK). Abstract, edited.]
Stillbirth during infection with Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
Daniel C. Payne 1, Ibrahim Iblan 2, Sultan Alqasrawi 3, Mohannad Al Nsour 4, Brian Rha 1,5, Rania A. Tohme 6, Glen R. Abedi 1, Noha H. Farag 7, Aktham Haddadin 8, Tarek Al Sanhouri 8, Najwa Jarour 3, David L. Swerdlow 1, Denise J. Jamieson 9, Mark A. Pallansch 1, Lia M. Haynes 1, Susan I. Gerber 1, Mohammad Mousa Al Abdallat 3, the Jordan MERS-CoV Investigation Team
Author Affiliations: <SUP>1</SUP>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA <SUP>2</SUP>Jordan Field Epidemiology Training Program, Amman, Jordan <SUP>3</SUP>Communicable Diseases Directorate, Jordan Ministry of Health, Amman, Jordan <SUP>4</SUP>Eastern Mediterranean Public Health Network (EMPHNET), Amman, Jordan <SUP>5</SUP>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA <SUP>6</SUP>Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA <SUP>7</SUP>Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA <SUP>8</SUP>Directorate of Laboratories, Jordan Ministry of Health, Amman, Jordan <SUP>9</SUP>Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Correspondence: Daniel C. Payne, PhD, MSPH (Tele) 404-639-2784 DVP6@CDC.GOV, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mailstop A-34, Atlanta, Georgia, 30333 U.S.A.
<CITE><ABBR>J Infect Dis.</ABBR> (2014) doi: 10.1093/infdis/jiu068 </CITE>First published online: January 28, 2014
Abstract
We conducted an epidemiologic investigation among survivors of a Middle East Respiratory Syndrome coronavirus (MERS-CoV) outbreak in Jordan. A second trimester stillbirth occurred during the course of an acute respiratory illness which was attributed to MERS-CoV, based on exposure history and positive MERS-CoV serology. This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV. Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy?related data, including biological specimens for confirmatory testing.
Received December 4, 2013. Revision received January 22, 2014. Accepted January 23, 2014.
Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.
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Stillbirth during infection with Middle East Respiratory Syndrome Coronavirus (MERS-CoV)
Daniel C. Payne 1, Ibrahim Iblan 2, Sultan Alqasrawi 3, Mohannad Al Nsour 4, Brian Rha 1,5, Rania A. Tohme 6, Glen R. Abedi 1, Noha H. Farag 7, Aktham Haddadin 8, Tarek Al Sanhouri 8, Najwa Jarour 3, David L. Swerdlow 1, Denise J. Jamieson 9, Mark A. Pallansch 1, Lia M. Haynes 1, Susan I. Gerber 1, Mohammad Mousa Al Abdallat 3, the Jordan MERS-CoV Investigation Team
Author Affiliations: <SUP>1</SUP>Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA <SUP>2</SUP>Jordan Field Epidemiology Training Program, Amman, Jordan <SUP>3</SUP>Communicable Diseases Directorate, Jordan Ministry of Health, Amman, Jordan <SUP>4</SUP>Eastern Mediterranean Public Health Network (EMPHNET), Amman, Jordan <SUP>5</SUP>Epidemic Intelligence Service, Centers for Disease Control and Prevention, Atlanta, Georgia, USA <SUP>6</SUP>Global Immunization Division, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA <SUP>7</SUP>Division of High Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA <SUP>8</SUP>Directorate of Laboratories, Jordan Ministry of Health, Amman, Jordan <SUP>9</SUP>Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Correspondence: Daniel C. Payne, PhD, MSPH (Tele) 404-639-2784 DVP6@CDC.GOV, Centers for Disease Control and Prevention, 1600 Clifton Road, NE, Mailstop A-34, Atlanta, Georgia, 30333 U.S.A.
<CITE><ABBR>J Infect Dis.</ABBR> (2014) doi: 10.1093/infdis/jiu068 </CITE>First published online: January 28, 2014
Abstract
We conducted an epidemiologic investigation among survivors of a Middle East Respiratory Syndrome coronavirus (MERS-CoV) outbreak in Jordan. A second trimester stillbirth occurred during the course of an acute respiratory illness which was attributed to MERS-CoV, based on exposure history and positive MERS-CoV serology. This is the first occurrence of stillbirth during an infection with MERS-CoV and may have bearing upon the surveillance and management of pregnant women in settings of unexplained respiratory illness potentially due to MERS-CoV. Future prospective investigations of MERS-CoV should ascertain pregnancy status and obtain further pregnancy?related data, including biological specimens for confirmatory testing.
Received December 4, 2013. Revision received January 22, 2014. Accepted January 23, 2014.
Published by Oxford University Press on behalf of the Infectious Diseases Society of America 2014. This work is written by (a) US Government employee(s) and is in the public domain in the US.
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