tetano
Editor, Senior Moderator
J Infect Chemother
. 2020 Sep 9;S1341-321X(20)30326-3.
doi: 10.1016/j.jiac.2020.09.006. Online ahead of print.
Effectiveness of personal protective equipment in preventing severe acute respiratory syndrome coronavirus 2 infection among healthcare workers
Tetsuya Suzuki[SUP] 1 [/SUP], Kayoko Hayakawa[SUP] 2 [/SUP], Akira Ainai[SUP] 3 [/SUP], Naoko Iwata-Yoshikawa[SUP] 3 [/SUP], Kaori Sano[SUP] 3 [/SUP], Noriyo Nagata[SUP] 3 [/SUP], Tadaki Suzuki[SUP] 3 [/SUP], Yuji Wakimoto[SUP] 2 [/SUP], Yutaro Akiyama[SUP] 2 [/SUP], Yusuke Miyazato[SUP] 2 [/SUP], Keiji Nakamura[SUP] 2 [/SUP], Satoshi Ide[SUP] 4 [/SUP], Hidetoshi Nomoto[SUP] 4 [/SUP], Takato Nakamoto[SUP] 2 [/SUP], Masayuki Ota[SUP] 2 [/SUP], Yuki Moriyama[SUP] 4 [/SUP], Yuko Sugiki[SUP] 5 [/SUP], Sho Saito[SUP] 4 [/SUP], Shinichiro Morioka[SUP] 4 [/SUP], Masahiro Ishikane[SUP] 2 [/SUP], Noriko Kinoshita[SUP] 4 [/SUP], Satoshi Kutsuna[SUP] 2 [/SUP], Norio Ohmagari[SUP] 4 [/SUP]
Affiliations
Abstract
Introduction: Information on the effectiveness of personal protective equipment (PPE) for preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among healthcare workers (HCWs), especially among HCWs with frequent contact with patients with SARS-CoV-2, is limited.
Methods: We conducted a prospective cohort study on 49 HCWs who worked in close contact with patients with SARS-CoV-2 infection. HCWs had blood samples taken every 2 weeks to test for SARS-CoV-2 antibodies using two different types of assay.
Results: Forty-nine participants (31 nurses, 15 doctors, 3 other workers) were enrolled. In total, 112 blood samples are obtained from participants. The median work days in 2 weeks was 9 (interquartile range (IQR): 5-10) days. In a single work day, 30 of the 49 participants (61.5%) had contact with patients with suspected or conformed SARS-CoV-2 at least 8 times, and approximately 60% of participants had more than 10 min of contact with a single patient. The median self-reported compliance to PPE was 90% (IQR: 80-100%). Seven participants tested positive for SARS-CoV-2 antibody using enzyme-linked immunosorbent assay (ELISA); however, none were seropositive for SARS-CoV-2 neutralizing antibody, so the positive ELISA results were assumed to be false-positive.
Conclusions: The study provides evidence that appropriate PPE is sufficient to prevent infection amongHCWs. It is necessary to establish a system that provides a stable supply of PPE for HCWs to perform their duties.
Keywords: COVID-19; Healthcare workers; Hospital-acquired infection; Personal protective equipment; SARS-CoV-2.
. 2020 Sep 9;S1341-321X(20)30326-3.
doi: 10.1016/j.jiac.2020.09.006. Online ahead of print.
Effectiveness of personal protective equipment in preventing severe acute respiratory syndrome coronavirus 2 infection among healthcare workers
Tetsuya Suzuki[SUP] 1 [/SUP], Kayoko Hayakawa[SUP] 2 [/SUP], Akira Ainai[SUP] 3 [/SUP], Naoko Iwata-Yoshikawa[SUP] 3 [/SUP], Kaori Sano[SUP] 3 [/SUP], Noriyo Nagata[SUP] 3 [/SUP], Tadaki Suzuki[SUP] 3 [/SUP], Yuji Wakimoto[SUP] 2 [/SUP], Yutaro Akiyama[SUP] 2 [/SUP], Yusuke Miyazato[SUP] 2 [/SUP], Keiji Nakamura[SUP] 2 [/SUP], Satoshi Ide[SUP] 4 [/SUP], Hidetoshi Nomoto[SUP] 4 [/SUP], Takato Nakamoto[SUP] 2 [/SUP], Masayuki Ota[SUP] 2 [/SUP], Yuki Moriyama[SUP] 4 [/SUP], Yuko Sugiki[SUP] 5 [/SUP], Sho Saito[SUP] 4 [/SUP], Shinichiro Morioka[SUP] 4 [/SUP], Masahiro Ishikane[SUP] 2 [/SUP], Noriko Kinoshita[SUP] 4 [/SUP], Satoshi Kutsuna[SUP] 2 [/SUP], Norio Ohmagari[SUP] 4 [/SUP]
Affiliations
- PMID: 32988731
- PMCID: PMC7480255
- DOI: 10.1016/j.jiac.2020.09.006
Abstract
Introduction: Information on the effectiveness of personal protective equipment (PPE) for preventing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection among healthcare workers (HCWs), especially among HCWs with frequent contact with patients with SARS-CoV-2, is limited.
Methods: We conducted a prospective cohort study on 49 HCWs who worked in close contact with patients with SARS-CoV-2 infection. HCWs had blood samples taken every 2 weeks to test for SARS-CoV-2 antibodies using two different types of assay.
Results: Forty-nine participants (31 nurses, 15 doctors, 3 other workers) were enrolled. In total, 112 blood samples are obtained from participants. The median work days in 2 weeks was 9 (interquartile range (IQR): 5-10) days. In a single work day, 30 of the 49 participants (61.5%) had contact with patients with suspected or conformed SARS-CoV-2 at least 8 times, and approximately 60% of participants had more than 10 min of contact with a single patient. The median self-reported compliance to PPE was 90% (IQR: 80-100%). Seven participants tested positive for SARS-CoV-2 antibody using enzyme-linked immunosorbent assay (ELISA); however, none were seropositive for SARS-CoV-2 neutralizing antibody, so the positive ELISA results were assumed to be false-positive.
Conclusions: The study provides evidence that appropriate PPE is sufficient to prevent infection amongHCWs. It is necessary to establish a system that provides a stable supply of PPE for HCWs to perform their duties.
Keywords: COVID-19; Healthcare workers; Hospital-acquired infection; Personal protective equipment; SARS-CoV-2.