tetano
Editor, Senior Moderator
J Infect Chemother
. 2020 Oct 16;S1341-321X(20)30378-0.
doi: 10.1016/j.jiac.2020.10.019. Online ahead of print.
Critically ill patients with COVID-19 in Tokyo, Japan: A single-center case series
Satoshi Miike[SUP] 1 [/SUP], Naoya Sakamoto[SUP] 2 [/SUP], Takuya Washino[SUP] 3 [/SUP], Atsushi Kosaka[SUP] 4 [/SUP], Yusuke Kuwahara[SUP] 5 [/SUP], Takuto Ishida[SUP] 6 [/SUP], Mayu Hikone[SUP] 7 [/SUP], Tatsunori Oyabu[SUP] 8 [/SUP], Hiroki Kojima[SUP] 9 [/SUP], Sentaro Iwabuchi[SUP] 10 [/SUP], Fukumi Nakamura-Uchiyama[SUP] 11 [/SUP]
Affiliations
Abstract
Introduction: We reported, in our previous study, a patient with coronavirus disease 2019 (COVID-19) who was successfully treated with extracorporeal membrane oxygenation. Data on clinical courses and outcomes of critically ill patients with COVID-19 in Japan are limited in the literature. This study aimed to describe the clinical courses and outcomes of critically ill patients with COVID-19 in Tokyo, Japan.
Methods: This is a single-center case series study. Patients with COVID-19 treated with mechanical ventilation (MV) were reviewed retrospectively. Data on baseline characteristics, in-hospital treatment, and outcomes were collected.
Results: Between February 2, 2020, and June 30, 2020, 14 critically ill patients with COVID-19 were treated with MV. Most patients were male and had comorbidities, especially hypertension or diabetes; 35.7% were overweight and 21.4% were obese. The majority of the patients had dyspnea on admission. The median duration of MV was 10.5 days, and the 28-day mortality rate was 35.7%. In the four patients with COVID-19 who died, the cause of death was respiratory failure.
Conclusions: As in previous reports from other countries, the mortality rate of patients with COVID-19 requiring intensive care remains high in Tokyo. Further study on the appropriate timing of MV initiation and specific treatments for critically ill patients with COVID-19 is needed.
Keywords: COVID-19; Coronavirus disease 2019; Mechanical ventilation; SARS-CoV-2.
. 2020 Oct 16;S1341-321X(20)30378-0.
doi: 10.1016/j.jiac.2020.10.019. Online ahead of print.
Critically ill patients with COVID-19 in Tokyo, Japan: A single-center case series
Satoshi Miike[SUP] 1 [/SUP], Naoya Sakamoto[SUP] 2 [/SUP], Takuya Washino[SUP] 3 [/SUP], Atsushi Kosaka[SUP] 4 [/SUP], Yusuke Kuwahara[SUP] 5 [/SUP], Takuto Ishida[SUP] 6 [/SUP], Mayu Hikone[SUP] 7 [/SUP], Tatsunori Oyabu[SUP] 8 [/SUP], Hiroki Kojima[SUP] 9 [/SUP], Sentaro Iwabuchi[SUP] 10 [/SUP], Fukumi Nakamura-Uchiyama[SUP] 11 [/SUP]
Affiliations
- PMID: 33121864
- DOI: 10.1016/j.jiac.2020.10.019
Abstract
Introduction: We reported, in our previous study, a patient with coronavirus disease 2019 (COVID-19) who was successfully treated with extracorporeal membrane oxygenation. Data on clinical courses and outcomes of critically ill patients with COVID-19 in Japan are limited in the literature. This study aimed to describe the clinical courses and outcomes of critically ill patients with COVID-19 in Tokyo, Japan.
Methods: This is a single-center case series study. Patients with COVID-19 treated with mechanical ventilation (MV) were reviewed retrospectively. Data on baseline characteristics, in-hospital treatment, and outcomes were collected.
Results: Between February 2, 2020, and June 30, 2020, 14 critically ill patients with COVID-19 were treated with MV. Most patients were male and had comorbidities, especially hypertension or diabetes; 35.7% were overweight and 21.4% were obese. The majority of the patients had dyspnea on admission. The median duration of MV was 10.5 days, and the 28-day mortality rate was 35.7%. In the four patients with COVID-19 who died, the cause of death was respiratory failure.
Conclusions: As in previous reports from other countries, the mortality rate of patients with COVID-19 requiring intensive care remains high in Tokyo. Further study on the appropriate timing of MV initiation and specific treatments for critically ill patients with COVID-19 is needed.
Keywords: COVID-19; Coronavirus disease 2019; Mechanical ventilation; SARS-CoV-2.