tetano
Editor, Senior Moderator
J Infect Chemother
. 2025 Jun 18:102760.
doi: 10.1016/j.jiac.2025.102760. Online ahead of print. Antiviral Treatment for Influenza in Japan
Tadashi Ishida[SUP] 1 [/SUP]
Affiliations
Anti-influenza drugs reduce the viral load, which leads to improvement of symptoms, a reduced illness period, suppression of complications, and protection from transmission. It is desirable to administer antiviral drugs within 48 hours of the onset of symptoms. The use of antiviral drugs is limited mainly to individuals who are hospitalized, those who have severe, complicated, or progressive illness, or those who are at high risk for influenza complications in western countries. On the other hand, in Japan, anti-influenza drugs have been widely used from the onset of the disease by general practitioners in order to ease symptoms, that leads to suppressed development of severe complications. Five drugs for influenza are available in Japan at present, which is thought to be that influenza treatment in Japan is the advanced one in the world. Baloxavir, the newest anti-influenza drug which has different mechanism from neuraminidase inhibitors rapidly reduce viral loads. Baloxavir is recommended as oseltamivir for the treatment of influenza.
Keywords: Anti-influenza drugs; Antiviral resistant virus; Baloxavir marboxil; Neuraminidase inhibitor.
. 2025 Jun 18:102760.
doi: 10.1016/j.jiac.2025.102760. Online ahead of print. Antiviral Treatment for Influenza in Japan
Tadashi Ishida[SUP] 1 [/SUP]
Affiliations
- PMID: 40541676
- DOI: 10.1016/j.jiac.2025.102760
Anti-influenza drugs reduce the viral load, which leads to improvement of symptoms, a reduced illness period, suppression of complications, and protection from transmission. It is desirable to administer antiviral drugs within 48 hours of the onset of symptoms. The use of antiviral drugs is limited mainly to individuals who are hospitalized, those who have severe, complicated, or progressive illness, or those who are at high risk for influenza complications in western countries. On the other hand, in Japan, anti-influenza drugs have been widely used from the onset of the disease by general practitioners in order to ease symptoms, that leads to suppressed development of severe complications. Five drugs for influenza are available in Japan at present, which is thought to be that influenza treatment in Japan is the advanced one in the world. Baloxavir, the newest anti-influenza drug which has different mechanism from neuraminidase inhibitors rapidly reduce viral loads. Baloxavir is recommended as oseltamivir for the treatment of influenza.
Keywords: Anti-influenza drugs; Antiviral resistant virus; Baloxavir marboxil; Neuraminidase inhibitor.