tetano
Editor, Senior Moderator
J Hosp Med
. 2020 Jul;15.
doi: 10.12788/jhm.3501.
Pooled Testing for SARS-CoV-2 in Hospitalized Patients
David Mastrianni[SUP] 1 [/SUP], Richard Falivena[SUP] 1 [/SUP], Timothy Brooks[SUP] 2 [/SUP], Brian McDermott[SUP] 3 [/SUP], Josenia Tan[SUP] 4 [/SUP], Richard Vandell[SUP] 4 [/SUP], Michael Holland[SUP] 5 [/SUP]
Affiliations
Abstract
Viral testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly early in the COVID-19 pandemic, was limited by supply of reagents. We pooled nasopharyngeal samples from patients at low risk of SARS-CoV-2 infection in groups of 3 for testing. Three weeks of testing using this strategy resulted in 530 patient tests in 179 cartridges; 4 positive test groups required the use of 11 additional cartridges with an overall positive rate of 0.8% in a low-risk population. This strategy resulted in the use of 340 fewer cartridges than if each test were performed on one patient sample. Pooled testing of low-risk populations allows for continued testing even when supplies are relatively scarce.
. 2020 Jul;15.
doi: 10.12788/jhm.3501.
Pooled Testing for SARS-CoV-2 in Hospitalized Patients
David Mastrianni[SUP] 1 [/SUP], Richard Falivena[SUP] 1 [/SUP], Timothy Brooks[SUP] 2 [/SUP], Brian McDermott[SUP] 3 [/SUP], Josenia Tan[SUP] 4 [/SUP], Richard Vandell[SUP] 4 [/SUP], Michael Holland[SUP] 5 [/SUP]
Affiliations
- PMID: 32816669
- DOI: 10.12788/jhm.3501
Abstract
Viral testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), particularly early in the COVID-19 pandemic, was limited by supply of reagents. We pooled nasopharyngeal samples from patients at low risk of SARS-CoV-2 infection in groups of 3 for testing. Three weeks of testing using this strategy resulted in 530 patient tests in 179 cartridges; 4 positive test groups required the use of 11 additional cartridges with an overall positive rate of 0.8% in a low-risk population. This strategy resulted in the use of 340 fewer cartridges than if each test were performed on one patient sample. Pooled testing of low-risk populations allows for continued testing even when supplies are relatively scarce.