tetano
Editor, Senior Moderator
J Geriatr Cardiol
. 2021 Jul 28;18(7):534-548.
doi: 10.11909/j.issn.1671-5411.2021.07.001.
Cardiovascular injuries and SARS-COV-2 infection: focus on elderly people
Claudia Colombo[SUP] 1 [/SUP], Laura Garatti[SUP] 1 2 [/SUP], Giulia Ferrante[SUP] 3 [/SUP], Francesca Casadei[SUP] 1 [/SUP], Claudio Montalto[SUP] 4 [/SUP], Gabriele Crimi[SUP] 5 [/SUP], Chiara Cogliati[SUP] 6 [/SUP], Enrico Ammirati[SUP] 7 [/SUP], Stefano Savonitto[SUP] 8 [/SUP], Nuccia Morici[SUP] 1 [/SUP]
Affiliations
Abstract
The novel coronavirus disease (COVID-19) has hit the healthcare system worldwide. The risk of severe infection and mortality increases with advancing age, especially in subjects with comorbidities such as cardiovascular disease, hypertension, diabetes, obesity and cancer. Moreover, cardiovascular complications such as myocardial injury, heart failure and thromboembolism are frequently observed in COVID-19 cases, and several biomarkers (troponin, NTproBNP and D-Dimer) have been identified as prognostic indicators of disease severity and worst outcome. Currently, there is no specific therapy against SARS-CoV-2, although many medications are under investigation. The aim of this review will be to explore the intertwined relationship between COVID-19 disease and the cardiovascular system, focusing on elderly population. The available supportive treatments along with the related concerns in elderly patients, due to their comorbidities and polypharmacotherapy, will be explored.
. 2021 Jul 28;18(7):534-548.
doi: 10.11909/j.issn.1671-5411.2021.07.001.
Cardiovascular injuries and SARS-COV-2 infection: focus on elderly people
Claudia Colombo[SUP] 1 [/SUP], Laura Garatti[SUP] 1 2 [/SUP], Giulia Ferrante[SUP] 3 [/SUP], Francesca Casadei[SUP] 1 [/SUP], Claudio Montalto[SUP] 4 [/SUP], Gabriele Crimi[SUP] 5 [/SUP], Chiara Cogliati[SUP] 6 [/SUP], Enrico Ammirati[SUP] 7 [/SUP], Stefano Savonitto[SUP] 8 [/SUP], Nuccia Morici[SUP] 1 [/SUP]
Affiliations
- PMID: 34404990
- PMCID: PMC8352775
- DOI: 10.11909/j.issn.1671-5411.2021.07.001
Abstract
The novel coronavirus disease (COVID-19) has hit the healthcare system worldwide. The risk of severe infection and mortality increases with advancing age, especially in subjects with comorbidities such as cardiovascular disease, hypertension, diabetes, obesity and cancer. Moreover, cardiovascular complications such as myocardial injury, heart failure and thromboembolism are frequently observed in COVID-19 cases, and several biomarkers (troponin, NTproBNP and D-Dimer) have been identified as prognostic indicators of disease severity and worst outcome. Currently, there is no specific therapy against SARS-CoV-2, although many medications are under investigation. The aim of this review will be to explore the intertwined relationship between COVID-19 disease and the cardiovascular system, focusing on elderly population. The available supportive treatments along with the related concerns in elderly patients, due to their comorbidities and polypharmacotherapy, will be explored.