tetano
Editor, Senior Moderator
J Asthma
. 2020 Dec 10;1-6.
doi: 10.1080/02770903.2020.1861622. Online ahead of print.
Severe asthma and COVID-19: lessons from the first wave
Patrucco Filippo[SUP] 1 2 [/SUP], Alida Benfante[SUP] 3 [/SUP], Elisa Villa[SUP] 4 [/SUP], Stefania Principe[SUP] 3 [/SUP], Nicola Scichilone[SUP] 3 [/SUP], Paolo Solidoro[SUP] 5 6 [/SUP]
Affiliations
Abstract
Objective: Severe asthma is considered a risk factor for SARS-Coronavirus 2 (SARS-CoV-2) infection but scientific evidences are lacking. Methods: we performed a literature search and review based on PubMed database national, international recommendations as well as papers on severe asthmatic patients and their management during SARS-CoV-2 pandemic. Results: the majority of international recommendations, expert panels and editorials provide indications about management of severe asthmatic patients. No published studies evaluated the effects of biologic agents on severe asthmatic patients during SARS-CoV-2 pandemic. Conclusions: the relationship between SARS-CoV-2 and asthma is variable worldwide and severe asthmatic patients were seldom reported in published cohorts. International recommendations suggest maintaining asthma under control to limit exacerbations occurrence, by using all available treatment. The minimum steroid dosage effective to control symptoms should be maintained to avoid exacerbations; biologic agents administration should be regularly scheduled encouraging patient support programmes.
Keywords: COVID-19; SARS-CoV-2; asthma; biologic agents; inhaled corticosteroids; oral corticosteroids; severe asthma.
. 2020 Dec 10;1-6.
doi: 10.1080/02770903.2020.1861622. Online ahead of print.
Severe asthma and COVID-19: lessons from the first wave
Patrucco Filippo[SUP] 1 2 [/SUP], Alida Benfante[SUP] 3 [/SUP], Elisa Villa[SUP] 4 [/SUP], Stefania Principe[SUP] 3 [/SUP], Nicola Scichilone[SUP] 3 [/SUP], Paolo Solidoro[SUP] 5 6 [/SUP]
Affiliations
- PMID: 33297799
- DOI: 10.1080/02770903.2020.1861622
Abstract
Objective: Severe asthma is considered a risk factor for SARS-Coronavirus 2 (SARS-CoV-2) infection but scientific evidences are lacking. Methods: we performed a literature search and review based on PubMed database national, international recommendations as well as papers on severe asthmatic patients and their management during SARS-CoV-2 pandemic. Results: the majority of international recommendations, expert panels and editorials provide indications about management of severe asthmatic patients. No published studies evaluated the effects of biologic agents on severe asthmatic patients during SARS-CoV-2 pandemic. Conclusions: the relationship between SARS-CoV-2 and asthma is variable worldwide and severe asthmatic patients were seldom reported in published cohorts. International recommendations suggest maintaining asthma under control to limit exacerbations occurrence, by using all available treatment. The minimum steroid dosage effective to control symptoms should be maintained to avoid exacerbations; biologic agents administration should be regularly scheduled encouraging patient support programmes.
Keywords: COVID-19; SARS-CoV-2; asthma; biologic agents; inhaled corticosteroids; oral corticosteroids; severe asthma.