Isolation and characterization of a novel H7N8 avian influenza virus from domestic ducks in Central China in 2017

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Virus Genes. 2019 Mar 20. doi: 10.1007/s11262-018-01630-2. [Epub ahead of print]
[h=1]Isolation and characterization of a novel H7N8 avian influenza virus from domestic ducks in Central China in 2017.[/h] Peng C[SUP]1[/SUP], Hou G[SUP]1[/SUP], Li J[SUP]1[/SUP], Cheng S[SUP]1[/SUP], Wang S[SUP]1[/SUP], Yi Y[SUP]2[/SUP], Chen J[SUP]3[/SUP], Jiang W[SUP]4[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] In 2017, an H7N8 avian influenza virus (AIV) was isolated from a domestic duck from a farm in Central China. Sequences analysis showed that this strain received its genes from H7, H1, H2, H3, H5, and H6 AIVs of domestic poultry and wild birds in Asia. It exhibited low pathogenicity in chickens and mild pathogenicity in mice. These results suggest the importance of continued surveillance of the H7N8 virus to better understand the ecology and evolution of the AIVs in poultry and wild birds and the potential threat to human health.


[h=4]KEYWORDS:[/h] Avian influenza virus; H7N8; Pathogenicity; Phylogenetic analysis; Reassortment

PMID: 30895439 DOI: 10.1007/s11262-018-01630-2