tetano
Editor, Senior Moderator
Behav Sleep Med. 2016 Apr 14:1-18. [Epub ahead of print]
Is Insomnia a Risk Factor for Decreased Influenza Vaccine Response?
Taylor DJ[SUP]1[/SUP], Kelly K[SUP]1[/SUP], Kohut ML[SUP]2[/SUP], Song KS[SUP]3[/SUP].
Author information
Abstract
Healthy young adult college students (N = 133) with Insomnia (n = 65) or No Insomnia (n = 68) were compared on influenza serum antibody levels pre- and four weeks postvaccination. Volunteers underwent structured clinical interviews for sleep disorders to ensure insomnia diagnoses, as well as psychiatric interviews, physical examinations, and drug testing to ensure comorbid health problems were not potential confounds. There were significant time (both groups had increases in antibody levels pre- to postvaccination) and group (Insomnia group had lower HI antibody levels overall) main effects, but the time x group interaction was nonsignificant. Exploratory analyses did find significant PSQI x Time (p < .001) and Insomnia Status x Time (p = .002) interaction effects. Results indicate insomnia may be a risk factor for lowered immunity to the influenza virus.
PMID: 27077395 [PubMed - as supplied by publisher]
Is Insomnia a Risk Factor for Decreased Influenza Vaccine Response?
Taylor DJ[SUP]1[/SUP], Kelly K[SUP]1[/SUP], Kohut ML[SUP]2[/SUP], Song KS[SUP]3[/SUP].
Author information
Abstract
Healthy young adult college students (N = 133) with Insomnia (n = 65) or No Insomnia (n = 68) were compared on influenza serum antibody levels pre- and four weeks postvaccination. Volunteers underwent structured clinical interviews for sleep disorders to ensure insomnia diagnoses, as well as psychiatric interviews, physical examinations, and drug testing to ensure comorbid health problems were not potential confounds. There were significant time (both groups had increases in antibody levels pre- to postvaccination) and group (Insomnia group had lower HI antibody levels overall) main effects, but the time x group interaction was nonsignificant. Exploratory analyses did find significant PSQI x Time (p < .001) and Insomnia Status x Time (p = .002) interaction effects. Results indicate insomnia may be a risk factor for lowered immunity to the influenza virus.
PMID: 27077395 [PubMed - as supplied by publisher]