tetano
Editor, Senior Moderator
Intern Med
. 2022 Jun 14.
doi: 10.2169/internalmedicine.9384-22. Online ahead of print.
Multisystem Inflammatory Syndrome in Adults Accompanied with Kikuchi-Fujimoto Disease: A Case Report
Eriko Kashihara[SUP] 1 2 3 [/SUP], Kosuke Doi[SUP] 1 4 [/SUP], Kohei Fujita[SUP] 1 5 [/SUP]
Affiliations
Abstract
We herein report a case of multisystem inflammatory syndrome in adults (MIS-A) complicated with Kikuchi-Fujimoto disease (KFD). A previously healthy 41-year-old man presented with painful swelling of the cervical lymph nodes, fever, diarrhea, conjunctivitis, edema, and hypotension one month after the onset of asymptomatic coronavirus disease 2019. Laboratory investigations revealed an elevation of CRP, and echocardiography indicated diastolic dysfunction. We diagnosed the patient to have MIS-A. Histopathology of the lymph nodes showed necrotizing lymphadenitis. After the initiation of hydrocortisone and diuretics, his symptoms resolved immediately. This case suggested that post-viral immune dysregulation in MIS-A could play a role in the etiology of KFD.
Keywords: COVID-19; Kikuchi-Fujimoto disease; SARS-CoV-2; multisystem inflammatory syndrome in adults.
. 2022 Jun 14.
doi: 10.2169/internalmedicine.9384-22. Online ahead of print.
Multisystem Inflammatory Syndrome in Adults Accompanied with Kikuchi-Fujimoto Disease: A Case Report
Eriko Kashihara[SUP] 1 2 3 [/SUP], Kosuke Doi[SUP] 1 4 [/SUP], Kohei Fujita[SUP] 1 5 [/SUP]
Affiliations
- PMID: 35705268
- DOI: 10.2169/internalmedicine.9384-22
Abstract
We herein report a case of multisystem inflammatory syndrome in adults (MIS-A) complicated with Kikuchi-Fujimoto disease (KFD). A previously healthy 41-year-old man presented with painful swelling of the cervical lymph nodes, fever, diarrhea, conjunctivitis, edema, and hypotension one month after the onset of asymptomatic coronavirus disease 2019. Laboratory investigations revealed an elevation of CRP, and echocardiography indicated diastolic dysfunction. We diagnosed the patient to have MIS-A. Histopathology of the lymph nodes showed necrotizing lymphadenitis. After the initiation of hydrocortisone and diuretics, his symptoms resolved immediately. This case suggested that post-viral immune dysregulation in MIS-A could play a role in the etiology of KFD.
Keywords: COVID-19; Kikuchi-Fujimoto disease; SARS-CoV-2; multisystem inflammatory syndrome in adults.