tetano
Editor, Senior Moderator
Int J Infect Dis
. 2020 May 10;S1201-9712(20)30333-7.
doi: 10.1016/j.ijid.2020.05.026. Online ahead of print.
Use of Anakinra in Severe COVID-19: A Case Report
Giovanni Filocamo[SUP] 1 [/SUP], Davide Mangioni[SUP] 2 [/SUP], Paola Tagliabue[SUP] 3 [/SUP], Stefano Aliberti[SUP] 4 [/SUP], Giorgio Costantino[SUP] 5 [/SUP], Francesca Minoia[SUP] 6 [/SUP], Alessandra Bandera[SUP] 7 [/SUP]
Affiliations
Abstract
Coronavirus Disease 19 is a global healthcare emergency with high lethality rate. Relevant inflammatory cytokine storm is associated with severity of disease and IL1 inhibition is a cornerstone treatment for hyperinflammatory diseases. We present here the case of a patient with critical COVID-19 successfully treated with IL-1 receptor antagonist (anakinra).
Keywords: Anakinra; Biologic; COVID-19; IL-1; Treatment.
Copyright ? 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.
. 2020 May 10;S1201-9712(20)30333-7.
doi: 10.1016/j.ijid.2020.05.026. Online ahead of print.
Use of Anakinra in Severe COVID-19: A Case Report
Giovanni Filocamo[SUP] 1 [/SUP], Davide Mangioni[SUP] 2 [/SUP], Paola Tagliabue[SUP] 3 [/SUP], Stefano Aliberti[SUP] 4 [/SUP], Giorgio Costantino[SUP] 5 [/SUP], Francesca Minoia[SUP] 6 [/SUP], Alessandra Bandera[SUP] 7 [/SUP]
Affiliations
- PMID: 32437934
- DOI: 10.1016/j.ijid.2020.05.026
Abstract
Coronavirus Disease 19 is a global healthcare emergency with high lethality rate. Relevant inflammatory cytokine storm is associated with severity of disease and IL1 inhibition is a cornerstone treatment for hyperinflammatory diseases. We present here the case of a patient with critical COVID-19 successfully treated with IL-1 receptor antagonist (anakinra).
Keywords: Anakinra; Biologic; COVID-19; IL-1; Treatment.
Copyright ? 2020 The Author(s). Published by Elsevier Ltd.. All rights reserved.