tetano
Editor, Senior Moderator
Int J Gynaecol Obstet
. 2023 Feb 6.
doi: 10.1002/ijgo.14714. Online ahead of print.
Interventions to Increase Uptake of Influenza Vaccination in Pregnancy: A Systematic Review and Meta-analysis
Eleonora Brillo[SUP] 1 2 [/SUP], Valentina Tosto[SUP] 1 [/SUP], Ersilia Buonomo[SUP] 2 [/SUP]
Affiliations
Abstract
Background: Maternal influenza vaccination has been introduced in several countries to prevent influenza-related morbidity and mortality in pregnant women, fetuses, and infants too young to be vaccinated.
Objectives: This systematic review and meta-analysis (CRD42021269478) aimed to analyze the available RCTs on the effectiveness of pregnant women-focused interventions to increase influenza vaccination uptake during pregnancy.
Search strategy: Medline, CINAHL, Scopus, Web of Science, and Cochrane Trial were searched on August 25, 2021.
Selection criteria: RCTs assessing the effectiveness of pregnant women-focused interventions in increasing influenza vaccination among pregnant women were included.
Data collection and analysis: Two independent reviewers extracted data. A random-effects meta-analysis was conducted to estimate pooled odds ratios (ORs).
Main results: Seven RCTs were selected. Overall, the interventions had a significant effect in increasing influenza vaccination during pregnancy compared to standard care (OR= 1.78 [1.25, 2.54]; P=0.001; I[SUP]2[/SUP] =67%). However, subgroup analysis suggested that influenza vaccination uptake only was associated with educational interventions (OR= 2.71 [1.93, 3.81]; P<0.001; I[SUP]2[/SUP] =0%).
Conclusions: We found that several educational interventions for pregnant women can effectively increase influenza vaccination uptake in this population. Specifically, pamphlets, websites, and brief one-to-one education can be effective tools.
Keywords: flu; immunization; influenza vaccine; interventions; maternal vaccination; pregnancy; strategies; vaccine hesitancy.
. 2023 Feb 6.
doi: 10.1002/ijgo.14714. Online ahead of print.
Interventions to Increase Uptake of Influenza Vaccination in Pregnancy: A Systematic Review and Meta-analysis
Eleonora Brillo[SUP] 1 2 [/SUP], Valentina Tosto[SUP] 1 [/SUP], Ersilia Buonomo[SUP] 2 [/SUP]
Affiliations
- PMID: 36748179
- DOI: 10.1002/ijgo.14714
Abstract
Background: Maternal influenza vaccination has been introduced in several countries to prevent influenza-related morbidity and mortality in pregnant women, fetuses, and infants too young to be vaccinated.
Objectives: This systematic review and meta-analysis (CRD42021269478) aimed to analyze the available RCTs on the effectiveness of pregnant women-focused interventions to increase influenza vaccination uptake during pregnancy.
Search strategy: Medline, CINAHL, Scopus, Web of Science, and Cochrane Trial were searched on August 25, 2021.
Selection criteria: RCTs assessing the effectiveness of pregnant women-focused interventions in increasing influenza vaccination among pregnant women were included.
Data collection and analysis: Two independent reviewers extracted data. A random-effects meta-analysis was conducted to estimate pooled odds ratios (ORs).
Main results: Seven RCTs were selected. Overall, the interventions had a significant effect in increasing influenza vaccination during pregnancy compared to standard care (OR= 1.78 [1.25, 2.54]; P=0.001; I[SUP]2[/SUP] =67%). However, subgroup analysis suggested that influenza vaccination uptake only was associated with educational interventions (OR= 2.71 [1.93, 3.81]; P<0.001; I[SUP]2[/SUP] =0%).
Conclusions: We found that several educational interventions for pregnant women can effectively increase influenza vaccination uptake in this population. Specifically, pamphlets, websites, and brief one-to-one education can be effective tools.
Keywords: flu; immunization; influenza vaccine; interventions; maternal vaccination; pregnancy; strategies; vaccine hesitancy.