tetano
Editor, Senior Moderator
Int J Gynaecol Obstet. 2020 Apr 24.
doi: 10.1002/ijgo.13182. Online ahead of print.A Systematic Scoping Review of COVID-19 During Pregnancy and Childbirth
Farida Elshafeey[SUP] 1 [/SUP], Rana Magdi[SUP] 1 [/SUP], Nader Hindi[SUP] 1 [/SUP], Mohamed Elshebiny[SUP] 1 [/SUP], Nourhan Farrag[SUP] 1 [/SUP], Shahd Mahdy[SUP] 1 [/SUP], Mohamed Sabbour[SUP] 1 [/SUP], Sara Gebril[SUP] 1 [/SUP], Mohamed Nasser[SUP] 1 [/SUP], Menna Kamel[SUP] 1 [/SUP], Abdelrahman Amir[SUP] 1 [/SUP], Moataz Maher Emara[SUP] 2 [/SUP], Ashraf Nabhan[SUP] 3 4 [/SUP]
Affiliations
Abstract
Background: Clinical presentation and outcomes of COVID-19 infection during pregnancy remain limited and fragmented.
Objectives: To summarize the existing literature on COVID-19 infection during pregnancy and childbirth, particularly concerning clinical presentation and outcomes.
Search strategy: A systematic search of LitCovid, EBSCO MEDLINE, CENTRAL, CINAHL, Web of Science, and Scopus electronic databases. The references of relevant studies were also searched.
Selection criteria: Identified titles and abstracts were screened to select original reports and cross-checked for overlap of cases.
Data collection and analysis: A descriptive summary organized by aspects of clinical presentations (symptoms, imaging, and laboratory) and outcomes (maternal and perinatal).
Main results: We identified 33 studies reporting 385 pregnant women with COVID-19 infection: 368 (95.6%) mild; 14 (3.6%) severe; and 3 (0.8%) critical. Seventeen women were admitted to intensive care, including six who were mechanically ventilated and one maternal mortality. A total of 252 women gave birth, comprising 175 (69.4%) cesarean and 77 (30.6%) vaginal births. Outcomes for 256 newborns included four RT-PCR positive neonates, two stillbirths, and one neonatal death.
Conclusion: COVID-19 infection during pregnancy probably has a clinical presentation and severity resembling that in non-pregnant adults. It is probably not associated with poor maternal or perinatal outcomes.
Keywords: COVID-19; Childbirth; Coronavirus; Neonate; Pregnancy; Systematic scoping review.
doi: 10.1002/ijgo.13182. Online ahead of print.A Systematic Scoping Review of COVID-19 During Pregnancy and Childbirth
Farida Elshafeey[SUP] 1 [/SUP], Rana Magdi[SUP] 1 [/SUP], Nader Hindi[SUP] 1 [/SUP], Mohamed Elshebiny[SUP] 1 [/SUP], Nourhan Farrag[SUP] 1 [/SUP], Shahd Mahdy[SUP] 1 [/SUP], Mohamed Sabbour[SUP] 1 [/SUP], Sara Gebril[SUP] 1 [/SUP], Mohamed Nasser[SUP] 1 [/SUP], Menna Kamel[SUP] 1 [/SUP], Abdelrahman Amir[SUP] 1 [/SUP], Moataz Maher Emara[SUP] 2 [/SUP], Ashraf Nabhan[SUP] 3 4 [/SUP]
Affiliations
- PMID: 32330287
- DOI: 10.1002/ijgo.13182
Abstract
Background: Clinical presentation and outcomes of COVID-19 infection during pregnancy remain limited and fragmented.
Objectives: To summarize the existing literature on COVID-19 infection during pregnancy and childbirth, particularly concerning clinical presentation and outcomes.
Search strategy: A systematic search of LitCovid, EBSCO MEDLINE, CENTRAL, CINAHL, Web of Science, and Scopus electronic databases. The references of relevant studies were also searched.
Selection criteria: Identified titles and abstracts were screened to select original reports and cross-checked for overlap of cases.
Data collection and analysis: A descriptive summary organized by aspects of clinical presentations (symptoms, imaging, and laboratory) and outcomes (maternal and perinatal).
Main results: We identified 33 studies reporting 385 pregnant women with COVID-19 infection: 368 (95.6%) mild; 14 (3.6%) severe; and 3 (0.8%) critical. Seventeen women were admitted to intensive care, including six who were mechanically ventilated and one maternal mortality. A total of 252 women gave birth, comprising 175 (69.4%) cesarean and 77 (30.6%) vaginal births. Outcomes for 256 newborns included four RT-PCR positive neonates, two stillbirths, and one neonatal death.
Conclusion: COVID-19 infection during pregnancy probably has a clinical presentation and severity resembling that in non-pregnant adults. It is probably not associated with poor maternal or perinatal outcomes.
Keywords: COVID-19; Childbirth; Coronavirus; Neonate; Pregnancy; Systematic scoping review.