tetano
Editor, Senior Moderator
J Clin Virol. 2013 Jun 25. pii: S1386-6532(13)00201-1. doi: 10.1016/j.jcv.2013.05.021. [Epub ahead of print]
Influenza virus A(H3N2) strain isolated from cerebrospinal fluid from a patient presenting myelopathy post infectious.
Paiva TM, Theotonio G, Paulino RS, Benega MA, Silva DB, Borborema SE, Ikeda TI, Kisielius JJ, Ueda M, Oliveira MI, Santos CL.
Source
N?cleo de Doen?as Respirat?rias, Instituto Adolfo Lutz, S?o Paulo, SP, Brazil. Electronic address: tterezinha@uol.com.br.
Abstract
BACKGROUND:
Neurological involvement during influenza infection has been described during epidemics and is often consistent with serious sequelae or death.
OBJECTIVE:
To investigate the etiologic agent involved in myelopathy post influenza-like syndrome.
STUDY DESIGN:
This investigation focuses on virus isolation from the cerebrospinal fluid (CSF) collected from a 19-year-old male student presenting with clinical diagnosis of myelopathy post influenza-like syndrome. To achieve this goal, different cell cultures and molecular methodologies were carried out.
RESULTS:
Influenza virus A(H3N2) strain was isolated in MDCK cell culture; virus particles were observed under electron microscopy. Phylogenetics analyses showed that the Brazilian influenza A(H3N2) strains were closely related to the A/Perth/16/2009-like.
CONCLUSION:
This study demonstrates that influenza virus A(H3N2) strain was the cause of illness of the students. According to the Brazilian influenza virus sentinel surveillance data A/Perth/16/2009-LIKE (H3N2) strain has predominated during the 2010 influenza virus season in Bras?lia - DF.
Copyright ? 2013 Elsevier B.V. All rights reserved.
PMID:
23809474
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23809474
Influenza virus A(H3N2) strain isolated from cerebrospinal fluid from a patient presenting myelopathy post infectious.
Paiva TM, Theotonio G, Paulino RS, Benega MA, Silva DB, Borborema SE, Ikeda TI, Kisielius JJ, Ueda M, Oliveira MI, Santos CL.
Source
N?cleo de Doen?as Respirat?rias, Instituto Adolfo Lutz, S?o Paulo, SP, Brazil. Electronic address: tterezinha@uol.com.br.
Abstract
BACKGROUND:
Neurological involvement during influenza infection has been described during epidemics and is often consistent with serious sequelae or death.
OBJECTIVE:
To investigate the etiologic agent involved in myelopathy post influenza-like syndrome.
STUDY DESIGN:
This investigation focuses on virus isolation from the cerebrospinal fluid (CSF) collected from a 19-year-old male student presenting with clinical diagnosis of myelopathy post influenza-like syndrome. To achieve this goal, different cell cultures and molecular methodologies were carried out.
RESULTS:
Influenza virus A(H3N2) strain was isolated in MDCK cell culture; virus particles were observed under electron microscopy. Phylogenetics analyses showed that the Brazilian influenza A(H3N2) strains were closely related to the A/Perth/16/2009-like.
CONCLUSION:
This study demonstrates that influenza virus A(H3N2) strain was the cause of illness of the students. According to the Brazilian influenza virus sentinel surveillance data A/Perth/16/2009-LIKE (H3N2) strain has predominated during the 2010 influenza virus season in Bras?lia - DF.
Copyright ? 2013 Elsevier B.V. All rights reserved.
PMID:
23809474
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23809474