tetano
Editor, Senior Moderator
Influenza Other Respir Viruses
. 2021 Jul 29.
doi: 10.1111/irv.12888. Online ahead of print.
Incidence rates of influenza illness during pregnancy in Suzhou, China, 2015-2018
Liling Chen[SUP] 1 [/SUP], Suizan Zhou[SUP] 2 [/SUP], Lin Bao[SUP] 1 [/SUP], Alexander J Millman[SUP] 2 [/SUP], Zhongwei Zhang[SUP] 3 [/SUP], Yan Wang[SUP] 4 [/SUP], Yayun Tan[SUP] 1 [/SUP], Ying Song[SUP] 2 [/SUP], Pengwei Cui[SUP] 1 [/SUP], Yuanyuan Pang[SUP] 1 [/SUP], Cheng Liu[SUP] 1 [/SUP], Jiangchun Qin[SUP] 1 [/SUP], Ping Zhang[SUP] 1 [/SUP], Mark G Thompson[SUP] 2 [/SUP], A Danielle Iuliano[SUP] 2 [/SUP], Ran Zhang[SUP] 2 [/SUP], Carolyn M Greene[SUP] 2 [/SUP], Jun Zhang[SUP] 1 [/SUP]
Affiliations
Abstract
Background: Data on influenza incidence during pregnancy in China are limited.
Methods: From October 2015 to September 2018, we conducted active surveillance for acute respiratory illness (ARI) among women during pregnancy. Nurses conducted twice weekly phone and text message follow-up upon enrollment until delivery to identify new episodes of ARI. Nasal and throat swabs were collected ≤10 days from illness onset to detect influenza.
Results: In total, we enrolled 18 724 pregnant women median aged 28 years old, 37% in first trimester, 48% in second trimester, and 15% in third trimester, with seven self-reported influenza vaccination during pregnancy. In the 18-week epidemic period during October 2015 to September 2016, influenza incidence was 0.7/100 person-months (95% CI: 0.5-0.9). In the cumulative 29-week-long epidemic during October 2016 to September 2017, influenza incidence was 1.0/100 person-months (95% CI: 0.8-1.2). In the 11-week epidemic period during October 2017 to September 2018, influenza incidence was 2.1/100 person-months (95% CI: 1.9-2.4). Influenza incidence was similar by trimester. More than half of the total influenza illnesses had no elevated temperature and cough. Most influenza-associated ARIs were mild, and <5.1% required hospitalization.
Conclusions: Influenza illness in all trimesters of pregnancy was common. These data may help inform decisions regarding the use of influenza vaccine to prevent influenza during pregnancy.
Keywords: active surveillance; cohort; incidence rate; influenza; pregnant women.
. 2021 Jul 29.
doi: 10.1111/irv.12888. Online ahead of print.
Incidence rates of influenza illness during pregnancy in Suzhou, China, 2015-2018
Liling Chen[SUP] 1 [/SUP], Suizan Zhou[SUP] 2 [/SUP], Lin Bao[SUP] 1 [/SUP], Alexander J Millman[SUP] 2 [/SUP], Zhongwei Zhang[SUP] 3 [/SUP], Yan Wang[SUP] 4 [/SUP], Yayun Tan[SUP] 1 [/SUP], Ying Song[SUP] 2 [/SUP], Pengwei Cui[SUP] 1 [/SUP], Yuanyuan Pang[SUP] 1 [/SUP], Cheng Liu[SUP] 1 [/SUP], Jiangchun Qin[SUP] 1 [/SUP], Ping Zhang[SUP] 1 [/SUP], Mark G Thompson[SUP] 2 [/SUP], A Danielle Iuliano[SUP] 2 [/SUP], Ran Zhang[SUP] 2 [/SUP], Carolyn M Greene[SUP] 2 [/SUP], Jun Zhang[SUP] 1 [/SUP]
Affiliations
- PMID: 34323381
- DOI: 10.1111/irv.12888
Abstract
Background: Data on influenza incidence during pregnancy in China are limited.
Methods: From October 2015 to September 2018, we conducted active surveillance for acute respiratory illness (ARI) among women during pregnancy. Nurses conducted twice weekly phone and text message follow-up upon enrollment until delivery to identify new episodes of ARI. Nasal and throat swabs were collected ≤10 days from illness onset to detect influenza.
Results: In total, we enrolled 18 724 pregnant women median aged 28 years old, 37% in first trimester, 48% in second trimester, and 15% in third trimester, with seven self-reported influenza vaccination during pregnancy. In the 18-week epidemic period during October 2015 to September 2016, influenza incidence was 0.7/100 person-months (95% CI: 0.5-0.9). In the cumulative 29-week-long epidemic during October 2016 to September 2017, influenza incidence was 1.0/100 person-months (95% CI: 0.8-1.2). In the 11-week epidemic period during October 2017 to September 2018, influenza incidence was 2.1/100 person-months (95% CI: 1.9-2.4). Influenza incidence was similar by trimester. More than half of the total influenza illnesses had no elevated temperature and cough. Most influenza-associated ARIs were mild, and <5.1% required hospitalization.
Conclusions: Influenza illness in all trimesters of pregnancy was common. These data may help inform decisions regarding the use of influenza vaccine to prevent influenza during pregnancy.
Keywords: active surveillance; cohort; incidence rate; influenza; pregnant women.