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Infect Chemother . Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in the Pleural Fluid

tetano

Editor, Senior Moderator
Infect Chemother


. 2020 Aug 10.
Online ahead of print.
Detection of Severe Acute Respiratory Syndrome Coronavirus 2 in the Pleural Fluid


Moon Seong Baek[SUP] 1 [/SUP], Won Young Kim[SUP] 1 [/SUP], Kyoung Ju Lee[SUP] 2 [/SUP], Chang Suk Noh[SUP] 3 [/SUP]



Affiliations
  • PMID: 32869550

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can be detected via a nasopharyngeal swab and in sputum, blood, urine, and feces. However, there is only limited data on the real-time reverse transcriptase polymerase chain reaction (RT-PCR) results of coronavirus disease 2019 (COVID-19) patients with pleural fluid. We report a case of COVID-19 with SARS-CoV-2 detected in both sputum and pleural fluid. A 68-year-old male patient came to the hospital with a chief complaint of dyspnea. He was diagnosed with lung cancer. A biopsy was performed, and a pneumothorax was found. As a result, a chest tube was placed into the right pleural space. During his hospital stay, the patient was confirmed as COVID-19 positive. We identified the presence of SARS-CoV-2 through real-time RT-PCR assay from the pleural fluid. Although pleural effusion is an uncommon finding in the COVID-19, care should be taken to avoid exposure when handling the pleural fluid sample.

Keywords: Coronavirus; Pleural effusion; Polymerase chain reaction.
 
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