Mary Wilson
Well-known member
17 JAN 2025. 6:50 PM ET
BY JON COHEN
doi: 10.1126/science.zs6ktjw
On 2 January, Japan’s regulatory agency issued a news release that startled some scientists: It had approved the antiviral drug tecovirimat, also known as TPOXX, for the treatment of mpox and two cousins, smallpox and cowpox.
No treatments exist for mpox, a painful and sometimes fatal disease now raging in sub-Saharan Africa, and tecovirimat initially looked promising: It prevented death in monkeys given lethal doses of mpox and smallpox virus. The European Unionand the United Kingdom both approved it in 2022, after an earlier epidemic of mpox in men who have sex with men (MSM). At the time, the drug had been shown to be safe in humans, but no efficacy data existed. ...
https://www.science.org/content/art...approves-mpox-drug-failed-two-efficacy-trials
BY JON COHEN
doi: 10.1126/science.zs6ktjw
On 2 January, Japan’s regulatory agency issued a news release that startled some scientists: It had approved the antiviral drug tecovirimat, also known as TPOXX, for the treatment of mpox and two cousins, smallpox and cowpox.
No treatments exist for mpox, a painful and sometimes fatal disease now raging in sub-Saharan Africa, and tecovirimat initially looked promising: It prevented death in monkeys given lethal doses of mpox and smallpox virus. The European Unionand the United Kingdom both approved it in 2022, after an earlier epidemic of mpox in men who have sex with men (MSM). At the time, the drug had been shown to be safe in humans, but no efficacy data existed. ...
https://www.science.org/content/art...approves-mpox-drug-failed-two-efficacy-trials