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Impact of influenza on outpatient visits and hospitalizations among pregnant women in Catalonia, Spain

tetano

Editor, Senior Moderator
J Infect. 2018 Jul 5. pii: S0163-4453(18)30211-1. doi: 10.1016/j.jinf.2018.06.015. [Epub ahead of print]
[h=1]Impact of influenza on outpatient visits and hospitalizations among pregnant women in Catalonia, Spain.[/h] Vilca LM[SUP]1[/SUP], Verma A[SUP]2[/SUP], Bonati M[SUP]3[/SUP], Campins M[SUP]4[/SUP].
[h=3]Author information[/h]

[h=3]Abstract[/h] [h=4]OBJECTIVE:[/h] To estimate outpatient visits and hospitalization rates due to cardiopulmonary illness attributable to influenza from 2008-09 to 2012-13 in a large cohort of pregnant women from Catalonia, Spain.
[h=4]METHODS:[/h] We estimated the event rates occurring during influenza epidemic, influenza non-epidemic and non-influenza seasons, and by pregnancy status (one year before pregnancy, first, second and third trimester). We fitted quasi-Poisson models in order to identify the variables associated to higher event rates.
[h=4]RESULTS:[/h] During influenza epidemic seasons, pregnant women in their second trimester had the highest rates of outpatient visits (153 per 10,000 women-months). An increased risk of outpatient visits was associated to first or second trimester (adjusted rate ratio (aRR)=1.17; 95% CI, 1.10-1.23 and aRR, 1.36; 95% CI, 1.28-1.43, respectively) and having any comorbidity (aRR=1.28; 95% CI, 1.21-1.36). Women during third trimester had the highest rates of hospitalizations (1.60 per 10,000 women-months), and an increased risk of hospitalization was significantly associated to third trimester (aRR, 1.85; 95% CI, 1.01-3.39), having any comorbidity (aRR, 1.93; 95% CI, 1.10-3.41) and the pandemic influenza season (aRR, 2.90 (1.81; 95% CI, 1.81-4.64).
[h=4]CONCLUSION:[/h] Our findings provide significant information regarding influenza burden of disease among pregnant women.
Copyright ? 2018. Published by Elsevier Ltd.


[h=4]KEYWORDS:[/h] Comorbidity; Hospitalization; Influenza; Outpatient visit; Pregnancy; Pregnancy trimesters

PMID: 29981774 DOI: 10.1016/j.jinf.2018.06.015
 
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