tetano
Editor, Senior Moderator
The Journal of Infectious Diseases 2010;201:1178?1182
? 2010 by the Infectious Diseases Society of America. All rights reserved.
0022-1899/2010/20108-0012$15.00
DOI: 10.1086/651507
BRIEF REPORT
Human Infection with a Triple‐Reassortant Swine Influenza A(H1N1) Virus Containing the Hemagglutinin and Neuraminidase Genes of Seasonal Influenza Virus
1National Microbiology Laboratory, Public Health Agency of Canada, and 2Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, and 3Saskatchewan Disease Control Laboratory, Regina, and 4Prince Albert Parkland Health Region, Prince Albert, Saskatchewan, Canada
A reassortant influenza A(H1N1) virus of swine origin distinct from the pandemic H1N1 2009 strain was isolated from 3 patients, all of whom worked at the same large hog operation in Saskatchewan, Canada. The genomic composition of the isolates has not been previously reported, to our knowledge, and was the product of a genetic reassortment between seasonal H1N1 and triple‐reassortant influenza virus that emerged in North American swine during the late 1990s. The neuraminidase and hemagglutinin genes of A/Saskatchewan/5350/2009, A/Saskatchewan/5351/2009, and A/Saskatchewan/5131/2009 were derived from human H1N1 virus and were closely related to those of A/Brisbane/59/2007.
http://www.journals.uchicago.edu/do...%7Cany%3A+influenza+h1n1%5D&searchHistoryKey=
? 2010 by the Infectious Diseases Society of America. All rights reserved.
0022-1899/2010/20108-0012$15.00
DOI: 10.1086/651507
BRIEF REPORT
Human Infection with a Triple‐Reassortant Swine Influenza A(H1N1) Virus Containing the Hemagglutinin and Neuraminidase Genes of Seasonal Influenza Virus
1National Microbiology Laboratory, Public Health Agency of Canada, and 2Department of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, and 3Saskatchewan Disease Control Laboratory, Regina, and 4Prince Albert Parkland Health Region, Prince Albert, Saskatchewan, Canada
A reassortant influenza A(H1N1) virus of swine origin distinct from the pandemic H1N1 2009 strain was isolated from 3 patients, all of whom worked at the same large hog operation in Saskatchewan, Canada. The genomic composition of the isolates has not been previously reported, to our knowledge, and was the product of a genetic reassortment between seasonal H1N1 and triple‐reassortant influenza virus that emerged in North American swine during the late 1990s. The neuraminidase and hemagglutinin genes of A/Saskatchewan/5350/2009, A/Saskatchewan/5351/2009, and A/Saskatchewan/5131/2009 were derived from human H1N1 virus and were closely related to those of A/Brisbane/59/2007.
http://www.journals.uchicago.edu/do...%7Cany%3A+influenza+h1n1%5D&searchHistoryKey=