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How quickly can antibiotic resistance spread?

Gert van der Hoek

In Memoriam - Editor, Senior Moderator
How quickly can antibiotic resistance spread? Consider the case of a Swedish man who traveled to India in 2009.
While in New Delhi, the man became infected by a strain of Klebsiella bacteria bearing a gene that made it impervious to the antibiotic carbapenem. Microbiologists quickly found the gene in bacterial samples from Mumbai as well.

In the span of just two years, it also turned up in Croatia, Pakistan, the United Kingdom, Canada, Japan and China.
“They found it everywhere,” Hanage said. “The cat was not just out of the bag; it had gotten out of the bag, made its way into the hamster cage, and was eating the hamsters.”

Today, the Centers for Disease Control and Prevention estimates that 9,000 U.S. patients per year are infected with carbapenem-resistant bacteria, causing 600 deaths annually.

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