tetano
Editor, Senior Moderator
Expert Rev Anti Infect Ther. 2013 Jun;11(6):555-63. doi: 10.1586/eri.13.40.
H1N1 pandemic: clinical and epidemiologic characteristics of the Canadian pediatric outbreak.
Fl?chelles O, Fowler R, Jouvet P.
Source
Pediatric ICU, Sainte-Justine Hospital, Montreal, QC, Canada.
Abstract
Canada was one of the first countries affected by the 2009 influenza H1N1 pandemic with two waves - one from May to June and one from October to December. The 2009 influenza H1N1 pandemic had many unique features when compared with seasonal influenza, including the following: more than half of the affected people were children; asthma was the most significant risk factor for hospital admission; and Aboriginal and pregnant women had a higher risk of hospital admission and complications. Antiviral therapy was widely used but data did not show any effect on the pediatric population. Outbreak spread was possibly promoted from child-child and child-adult contact, and therefore the vaccination campaign targeted the pediatric population and achieved good coverage among young children (57%). Vaccination efficacy was difficult to test because of the vaccination delay. Improvement in models of prevention and treatment are urgently needed to prepare for the possible future pandemics.
PMID:
23750727
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23750727
H1N1 pandemic: clinical and epidemiologic characteristics of the Canadian pediatric outbreak.
Fl?chelles O, Fowler R, Jouvet P.
Source
Pediatric ICU, Sainte-Justine Hospital, Montreal, QC, Canada.
Abstract
Canada was one of the first countries affected by the 2009 influenza H1N1 pandemic with two waves - one from May to June and one from October to December. The 2009 influenza H1N1 pandemic had many unique features when compared with seasonal influenza, including the following: more than half of the affected people were children; asthma was the most significant risk factor for hospital admission; and Aboriginal and pregnant women had a higher risk of hospital admission and complications. Antiviral therapy was widely used but data did not show any effect on the pediatric population. Outbreak spread was possibly promoted from child-child and child-adult contact, and therefore the vaccination campaign targeted the pediatric population and achieved good coverage among young children (57%). Vaccination efficacy was difficult to test because of the vaccination delay. Improvement in models of prevention and treatment are urgently needed to prepare for the possible future pandemics.
PMID:
23750727
[PubMed - in process]
http://www.ncbi.nlm.nih.gov/pubmed/23750727